Ginsenoside Rf, a trace component of ginseng root, produces antinociception in mice

JS Mogil, YH Shin, EW McCleskey, SC Kim, SY Nah - Brain research, 1998 - Elsevier
Ginseng root, a traditional oriental medicine, contains more than a dozen biologically active
saponins called ginsenosides, including one present in only trace amounts called …

Ginseng and ginsenoside Rg3, a newly identified active ingredient of ginseng, modulate Ca2+ channel currents in rat sensory neurons

H Rhim, H Kim, DY Lee, TH Oh, SY Nah - European journal of …, 2002 - Elsevier
There is increasing evidence that ginseng influences pain modulation. In spite of extensive
behavior studies, the detailed mechanism of ginseng actions at the cellular level and the …

Effect of ginsenosides, active components of ginseng, on capsaicin-induced pain-related behavior

JJ Nah, JH Hahn, S Chung, S Choi, YI Kim, SY Nah - Neuropharmacology, 2000 - Elsevier
Our recent study demonstrated that ginsenosides had antinociceptive effects by reducing
some types of pain-related behavior in mice (Yoon et al., 1998. Ginsenosides induce …

Ginsenosides that produce differential antinociception in mice

YH Shin, OM Jung, JJ Nah, KY Nam, CY Kim… - … : The Vascular System, 1999 - Elsevier
Ginsenoside Rc, Rd, and Re induced antinociception in writhing and formalin tests among
five representative ginsenosides: Rb1, Rc, Rd, Re, and Rg1. However, these ginsenosides …

Ginseng root extract inhibits calcium channels in rat sensory neurons through a similar path, but different receptor, as μ-type opioids

SY Nah, EW McCleskey - Journal of ethnopharmacology, 1994 - Elsevier
The effect of Panax ginseng root extract on Ca 2+ current of adult rat trigeminal ganglion
neurons was investigated using whole-cell patch-clamp methods. The application of P …

[HTML][HTML] Antinociceptive and anti-inflammatory effects of ginsenoside Rf in a rat model of incisional pain

MK Kim, H Kang, CW Baek, YH Jung, YC Woo… - Journal of Ginseng …, 2018 - Elsevier
Background Ginseng saponin has long been used as a traditional Asian medicine and is
known to be effective in treating various kinds of pain. Ginsenoside Rf is one of the …

Ginsenosides induce differential antinociception and inhibit substance P induced-nociceptive response in mice

SR Yoon, JJ Nah, YH Shin, SK Kim, KY Nam, HS Choi… - Life sciences, 1998 - Elsevier
Ginsenosides are main pharmacoactive molecules of ginseng. The antinociceptive activity of
ginsenosides after intrathecal (it) injection was examined in formalin test. We also …

Ginsenosides: are any of them candidates for drugs acting on the central nervous system?

SY Nah, DH Kim, H Rhim - CNS drug reviews, 2007 - Wiley Online Library
The last two decades have shown a marked expansion in the number of publications
regarding the effects of Panax ginseng. Ginsenosides, which are unique saponins isolated …

Effects of ginsenoside Rg2 on human neuronal nicotinic acetylcholine receptors

F Sala, J Mulet, S Choi, SY Jung, SY Nah… - … of Pharmacology and …, 2002 - ASPET
Ginseng saponins, major active components of ginseng root used by folk medicine in the
treatment of various diseases, produce multiple pharmacological responses having many …

[HTML][HTML] Effects of ginsenosides on vanilloid receptor (VR1) channels expressed in Xenopus oocytes

SY Jung, S Choi, YS Ko, CS Park, S Oh, SR Koh… - Molecules and cells, 2001 - Elsevier
Ginsenosides, or ginseng saponins, are biologically active ingredients of Panax ginseng.
Accumulating evidence suggests that ginsenosides can alleviate pain from injections of …