Does the sympathetic nervous system adapt to chronic altitude exposure?
M Sander - Hypoxia: Translation in Progress, 2016 - Springer
During continued exposure to hypobaric hypoxia in acclimatizing lowlanders increasing
norepinephrine levels indirectly indicate sympathoexcitation, and in a few subjects serial …
norepinephrine levels indirectly indicate sympathoexcitation, and in a few subjects serial …
Sustained sympathetic activity in altitude acclimatizing lowlanders and high‐altitude natives
C Lundby, J Calbet, G Van Hall… - … journal of medicine & …, 2018 - Wiley Online Library
Combined results from different independent studies suggest that acclimatization to high
altitude induces a slowly developing sympathetic activation, even at levels of hypoxia that …
altitude induces a slowly developing sympathetic activation, even at levels of hypoxia that …
Carotid chemoreceptor control of muscle sympathetic nerve activity in hypobaric hypoxia
New Findings What is the central question of this study? High‐altitude hypoxia increases
muscle sympathetic nerve activity (MSNA), but whether intravenous infusion of dopamine, to …
muscle sympathetic nerve activity (MSNA), but whether intravenous infusion of dopamine, to …
Sympathetic neural overactivity in healthy humans after prolonged exposure to hypobaric hypoxia
J Hansen, M Sander - The Journal of physiology, 2003 - Wiley Online Library
Acute exposure to hypoxia causes chemoreflex activation of the sympathetic nervous
system. During acclimatization to high altitude hypoxia, arterial oxygen content recovers, but …
system. During acclimatization to high altitude hypoxia, arterial oxygen content recovers, but …
Human autonomic activity and its response to acute oxygen supplement after high altitude acclimatization
X Bao, BP Kennedy, SR Hopkins, HJ Bogaard… - Autonomic …, 2002 - Elsevier
It is well established that after acclimatization at high altitude, many sympathetic pathways
are hyperactive yet heart rate (HR) remains unchanged. In this study, we attempted to …
are hyperactive yet heart rate (HR) remains unchanged. In this study, we attempted to …
Reduced autonomic activity during stepwise exposure to high altitude
K Sevre, B Bendz, E Hankø, AR Nakstad… - Acta Physiologica …, 2001 - Wiley Online Library
Several studies have shown increased sympathetic activity during acute exposure to
hypobaric hypoxia. In a recent field study we found reduced plasma catecholamines during …
hypobaric hypoxia. In a recent field study we found reduced plasma catecholamines during …
Acclimatization to high altitude increase muscle sympathetic activity both at rest and during exercise
RS Mazzeo, GA Brooks, GE Butterfield… - American Journal …, 1995 - journals.physiology.org
This investigation examined the relationship between alterations in plasma norepinephrine
associated with 21 days of high-altitude exposure and muscle sympathetic activity both at …
associated with 21 days of high-altitude exposure and muscle sympathetic activity both at …
Mechanisms underpinning sympathoexcitation in hypoxia
LL Simpson, M Stembridge… - The Journal of …, 2024 - Wiley Online Library
Sympathoexcitation is a hallmark of hypoxic exposure, occurring acutely, as well as
persisting in acclimatised lowland populations and with generational exposure in highland …
persisting in acclimatised lowland populations and with generational exposure in highland …
Influence of recent altitude exposure on sea level sympathetic neural & hemodynamic responses to orthostasis
KM Mitchell, KE Bradbury, AM Posch… - Autonomic …, 2018 - Elsevier
Although it has been shown that muscle sympathetic nerve activity increases during high
altitude exposure, mechanisms of sympathoexcitation and blood pressure control after …
altitude exposure, mechanisms of sympathoexcitation and blood pressure control after …
Sympathetic response during 21 days at high altitude (4,300 m) as determined by urinary and arterial catecholamines
RS Mazzeo, EE Wolfel, GE Butterfield, JT Reeves - Metabolism, 1994 - Elsevier
The sympathoadrenal system plays a major role in adjustments to both short-and long-term
high-altitude exposure. Thus, this study investigated catecholamine responses in blood …
high-altitude exposure. Thus, this study investigated catecholamine responses in blood …