Immunogenicity of a vaccine formulated with the Chlamydia trachomatis serovar F, native major outer membrane protein in a nonhuman primate model

C Cheng, S Pal, I Bettahi, KL Oxford, PA Barry… - Vaccine, 2011 - Elsevier
To determine the ability of a vaccine formulated with the genital Chlamydia trachomatis,
serovar F, native major outer membrane protein (Ct-F-nMOMP), to induce systemic and …

Immunization with the Chlamydia trachomatis major outer membrane protein, using adjuvants developed for human vaccines, can induce partial protection in a mouse …

S Pal, EM Peterson, R Rappuoli, G Ratti… - Vaccine, 2006 - Elsevier
To test several vaccines for Chlamydia trachomatis we vaccinated BALB/c and C3H/HeN
female mice with a purified preparation of the native mouse pneumonitis (MoPn) major outer …

Protection against an intranasal challenge by vaccines formulated with native and recombinant preparations of the Chlamydia trachomatis major outer membrane …

G Sun, S Pal, J Weiland, EM Peterson, LM de la Maza - Vaccine, 2009 - Elsevier
To compare the ability of a native and a recombinant preparation of the major outer
membrane protein of Chlamydia trachomatis mouse pneumonitis (MoPn; Ct-nMOMP and Ct …

Protective efficacy of a parenterally administered MOMP-derived synthetic oligopeptide vaccine in a murine model of Chlamydia trachomatis genital tract infection …

H Su, M Parnell, HD Caldwell - Vaccine, 1995 - Elsevier
The protective efficacy of an alum-adsorbed, parenterally administered synthetic
oligopeptide immunogen corresponding to antigenically common T-helper and neutralizing …

Vaccination with the Chlamydia trachomatis Major Outer Membrane Protein Can Elicit an Immune Response as Protective as That Resulting from Inoculation with …

S Pal, EM Peterson, LM de la Maza - Infection and immunity, 2005 - Am Soc Microbiol
ABSTRACT BALB/c mice were vaccinated by the intramuscular (im) and subcutaneous (sc)
routes with a native preparation of the Chlamydia trachomatis mouse pneumonitis (MoPn) …

Comparison of the nine polymorphic membrane proteins of Chlamydia trachomatis for their ability to induce protective immune responses in mice against a C …

S Pal, A Favaroni, DF Tifrea, PT Hanisch, SET Luczak… - Vaccine, 2017 - Elsevier
Objectives To test vaccines, formulated with novel antigens, to protect mice against
Chlamydia infections. Methods To determine the ability of polymorphic membrane proteins …

Enhancement of the protective efficacy of a Chlamydia trachomatis recombinant vaccine by combining systemic and mucosal routes for immunization

P Ralli-Jain, D Tifrea, C Cheng, S Pal, LM De la Maza - Vaccine, 2010 - Elsevier
Chlamydia trachomatis causes respiratory and sexually transmitted infections. Here, we
tested a vaccine formulated with the recombinant major outer membrane protein from C …

CD4+ T Cells and Antibody Are Required for Optimal Major Outer Membrane Protein Vaccine-Induced Immunity to Chlamydia muridarum Genital Infection

CM Farris, SG Morrison, RP Morrison - Infection and immunity, 2010 - Am Soc Microbiol
Despite effective antimicrobial chemotherapy, control of Chlamydia trachomatis urogenital
infection will likely require a vaccine. We have assessed the protective effect of an outer …

Protection against genital tract Chlamydia trachomatis infection following intranasal immunization with a novel recombinant MOMP VS2/4 antigen

R Hadad, E Marks, I Kalbina, K Schön, M Unemo… - APMIS, 2016 - Wiley Online Library
The asymptomatic nature of most Chlamydia trachomatis infections and the lack of
appropriate effects by current prevention and management call for vaccine development. We …

[HTML][HTML] Vaccination with the recombinant major outer membrane protein elicits long-term protection in mice against vaginal shedding and infertility following a …

S Pal, MI Cruz-Fisher, C Cheng, JR Carmichael… - NPJ vaccines, 2020 - nature.com
Implementation of a vaccine is likely the best approach to curtail Chlamydia trachomatis
infections. The aim of this study was to determine the ability of a vaccine formulated with the …