Modulation of Estrogen Oxidative Metabolism by Botanicals (Hops and Licorice) Used for Women's Health

S Wang - 2017 - indigo.uic.edu
Estrogen is the primary hormone in women that plays an important role in maintaining
normal functions of various tissues and organs. However, elongated exposure to estrogen …

Modulation of estrogen chemical carcinogenesis by botanical supplements used for postmenopausal women's health

CS Snelten, B Dietz, JL Bolton - Drug Discovery Today: Disease …, 2012 - Elsevier
Breast cancer risk has been associated with long-term estrogen exposure including
traditional hormone therapy (HT, formally hormone replacement therapy). To avoid …

Mechanisms of estrogen carcinogenesis: modulation by botanical natural products

JL Bolton - Chemical Carcinogenesis, 2010 - Springer
The longer women are exposed to estrogens, through early menarche and late menopause
and/or through hormone replacement therapy (HRT), the higher is the risk of developing …

The Role of Botanicals and Their AhR-Active Compounds in Estrogen Chemical Carcinogenesis

RT Hitzman - 2021 - search.proquest.com
Botanical dietary supplements (BDS) are increasingly popular and may provide resilience in
women. Women's health BDS were initially evaluated for an ability to influence the estrogen …

Red clover aryl hydrocarbon receptor (AhR) and estrogen receptor (ER) agonists enhance genotoxic estrogen metabolism

TL Dunlap, CE Howell, N Mukand… - Chemical research in …, 2017 - ACS Publications
Many women consider botanical dietary supplements (BDSs) as safe alternatives to
hormone therapy for menopausal symptoms. However, the effect of BDSs on breast cancer …

Hops (Humulus lupulus) Inhibits Oxidative Estrogen Metabolism and Estrogen-Induced Malignant Transformation in Human Mammary Epithelial cells (MCF-10A)

LP Hemachandra, P Madhubhani… - Cancer prevention …, 2012 - AACR
Long-term exposure to estrogens including those in traditional hormone replacement
therapy (HRT) increases the risk of developing hormone-dependent cancers. As a result …

Modulation of Estrogen Metabolism by Hops Extracts and Bioactive Compounds as Analyzed by LC-MS-MS

CS Snelten - 2013 - indigo.uic.edu
The oxidative metabolism of estrogens into estrogen quinones that damage DNA,
contributes to the carcinogenicity of estrogens. In order to circumvent using hormone …

[图书][B] The actions of estrogen metabolites and phytoestrogens in breast carcinogenesis—Mechanistic insights from in vitro and in vivo studies

SM Mense - 2009 - search.proquest.com
Steroidal estrogens are suggested to induce breast cancer by way of a two-tiered
mechanism, in which estrogens stimulate cell growth and proliferation and generate …

Prevention of Estrogen Carcinogenesis by Botanicals, SERMs and NO/cGMP Pathway Modulators

LPMP Hemachandra - 2013 - search.proquest.com
Breast cancer is a major hormone dependent cancer which is the second leading cause of
cancer death among women. In order to discover new preventive measures for breast …

Can women's health botanicals prevent estrogen carcinogenesis?

BM Dietz, TL Dunlap, A Hajirahimkhan, S Wang… - Planta …, 2015 - thieme-connect.com
Breast cancer is the second most common malignancy among women becoming even more
prevalent with age. Three major pathways are considered to be important in estrogen …