Background Acute kidney injury (AKI) is an emerging global healthcare issue without
effective therapy yet. Autophagy recycles damaged organelles and helps maintain tissue …

Abstract Background Mesenchymal stem cells (MSCs) have been reported to promote the
regeneration of injured tissue via their paracrine abilities, which are enhanced by hypoxic …

Background: Renal ischemia followed by reperfusion leads to acute renal failure in both
native kidneys and renal allograft. This study aimed at investigating the effects …

Background Reactive oxygen species are important mediators exerting toxic effects on
various organs during ischemia-reperfusion (IR) injury. We hypothesized that adipose …

To confer further therapeutic potential and prevent some adverse effects by the
mesenchymal stem cells (MSCs) transplantation, we explored the effects of locally intrarenal …

Hypoxia preconditioning has been confirmed as an effective strategy to enhance the
therapeutic potentials of mesenchymal stem cells (MSCs), such as for myocardial ischemia …

Acute kidney injury (AKI) causes a lot of harm to human health but is treated by only
supportive therapy in most cases. Recent evidence shows that mesenchymal stem cells …

Background aims. Ischemia-reperfusion (IR) injury is a common cause of acute renal failure.
Bone marrow (BM)-derived mesenchymal stromal cells (MSC) delivered after renal IR are …

The mortality of rhabdomyolysis-induced AKI remains high because no effective therapy
exists. We investigated a new therapeutic method using MSCs. The aim of this study was to …

Acute kidney injury (AKI) is a rapid loss of renal function. It has high mortality rates. Still,
renal replacement therapy is considered the best solution for recovering AKI. This opens a …