Ischemia-reperfusion injury (IRI) plays a significant role in the pathogenesis of acute kidney
injury (AKI). The complicated interaction between injured tubular cells, activated endothelial …

Mitochondria take part in a network of cellular processes that regulate cell homeostasis.
Defects in mitochondrial function are key pathophysiological changes during acute kidney …

Background Acute kidney injury (AKI) leads to serious renal damage, and early inhibition of
inflammation is necessary for its treatment. C5a/C5aR signaling activation promotes …

Although previous and ongoing clinical studies have used stromal cells during renal
ischemia-reperfusion injury (IRI), there is little consensus regarding the optimal protocol. We …

Abstract Background Mesenchymal stromal cells (MSCs) represent an option for the
treatment of acute kidney injury (AKI). It is known that young stem cells are better than are …

Acute kidney injury (AKI) is a common, severe emergency case in clinics, with high
incidence, significant mortality and increased costs. Despite development in the …

Introduction This study tested the hypothesis that cyclosporine (CsA)-supported syngeneic
adipose-derived mesenchymal stem cell (ADMSC) therapy offered superior attenuation of …

Administration of fibroblastic cells derived from a number of tissues (collectively called
“mesenchymal stem cells”) has been suggested to be beneficial for renal repair and …

Background/Aims: Anti-oxidation is an effective strategy for curing acute kidney injury (AKI).
Herein, we suggest that extracellular vesicles (EVs) derived from mesenchymal stromal cells …

Acute kidney injury (AKI) is classically described as a rapid loss of kidney function. AKI
affects more than 15% of all hospital admissions and is associated with elevated mortality …