The protective actions of tanshinones on hypoxia‐induced cell damages have been
reported, although the mechanisms have not been fully elucidated. Given the importance of …

Mitochondrial apoptosis pathway is an important target of cardioprotective signalling.
Tanshinones, a group of major bioactive compounds isolated from Salvia miltiorrhiza, have …

Tanshinone IIA is an important component that is isolated from danshen (Salvia miltiorrhiza),
which is known to be beneficial for cardiovascular health. In this study, we determined the …

Myocardial ischemia triggers an inflammatory reaction and oxidative stress that increases
apoptosis of myocardiocytes. It has been evidenced that tanshinone‑IIA (Tan‑IIA) protects …

Background Acute myocardial injury (AMI), which is induced by renal ischemia-reperfusion
(IR), is a significant cause of acute kidney injury (AKI)-related associated death. Obesity …

Objective To determine the mechanism by which Tanshinone IIA (Tan IIA) relieves
myocardial ischemia reperfusion injury (MIRI) in rats via the PI3K/Akt/mTOR signaling …

The purpose of the present study was to evaluate whether tanshinone IIA (TIIA) could treat
cardiac dysfunction and fibrosis in heart failure (HF) by inhibiting oxidative stress. An HF …

Context: Foliol, linearol, and sidol are the most common diterpenes found in Sideritis L.
spp.(Lamiaceae) with a wide range of demonstrated properties including anti-inflammatory …

Oxidative stress has been widely implicated in the pathogenesis of hypoxia/reoxygenation
(H/R) injury. San-Huang-Xie-Xin-Tang (SHXT), a widely used traditional Chinese …

Abstract Tanshinone I (TI; C 18 H 12 O 3) is a cytoprotective molecule. TI has been viewed
as an antioxidant and anti-inflammatory agent exerting neuroprotective actions in several …