Identification of App1 as a regulator of phagocytosis and virulence of Cryptococcus neoformans
C Luberto, B Martinez-Mariño… - The Journal of …, 2003 - Am Soc Clin Investig
Cryptococcus neoformans is a fungal pathogen that, after inhalation, can disseminate to the
brain. Host alveolar macrophages (AMs) represent the first defense against the fungus …
brain. Host alveolar macrophages (AMs) represent the first defense against the fungus …
Role of glucose in the expression of Cryptococcus neoformans antiphagocytic protein 1, App1
V Williams, M Del Poeta - Eukaryotic cell, 2011 - Am Soc Microbiol
The cryptococcus-specific protein antiphagocytic protein 1 (App1) regulates Cryptococcus
neoformans virulence by controlling macrophage-driven fungal phagocytosis. This is …
neoformans virulence by controlling macrophage-driven fungal phagocytosis. This is …
Paradoxical roles of alveolar macrophages in the host response to Cryptococcus neoformans
TJ McQuiston, PR Williamson - Journal of Infection and Chemotherapy, 2012 - Elsevier
Cryptococcus neoformans (Cn) is a fungal pathogen that is a serious health threat to
immunocompromised individuals. Upon environmental exposure, infectious fungal …
immunocompromised individuals. Upon environmental exposure, infectious fungal …
Cryptococcus and Phagocytes: Complex Interactions that Influence Disease Outcome
Cryptococcus neoformans and C. gattii are fungal pathogens that cause life-threatening
disease. These fungi commonly enter their host via inhalation into the lungs where they …
disease. These fungi commonly enter their host via inhalation into the lungs where they …
Dangerous Liaisons: Interactions of Cryptococcus neoformans with Host Phagocytes
EA Gaylord, HL Choy, TL Doering - Pathogens, 2020 - mdpi.com
Cryptococcus neoformans is an opportunistic fungal pathogen and a leading cause of death
in immunocompromised individuals. The interactions of this yeast with host phagocytes are …
in immunocompromised individuals. The interactions of this yeast with host phagocytes are …
Surface-Associated Plasminogen Binding of Cryptococcus neoformans Promotes Extracellular Matrix Invasion
J Stie, G Bruni, D Fox - PloS one, 2009 - journals.plos.org
Background The fungal pathogen Cryptococcus neoformans is a leading cause of illness
and death in persons with predisposing factors, including: malignancies, solid organ …
and death in persons with predisposing factors, including: malignancies, solid organ …
Pulmonary Macrophage and Dendritic Cell Responses to Cryptococcus neoformans
BN Nelson, AN Hawkins, KL Wozniak - Frontiers in cellular and …, 2020 - frontiersin.org
The fungal pathogen Cryptococcus neoformans can cause life-threatening infections in
immune compromised individuals. This pathogen is typically acquired via inhalation, and …
immune compromised individuals. This pathogen is typically acquired via inhalation, and …
Catch me if you can: phagocytosis and killing avoidance by Cryptococcus neoformans
R Garcia-Rodas, O Zaragoza - FEMS Immunology & Medical …, 2012 - academic.oup.com
After inhalation of infectious particles, Cryptococcus neoformans resides in the alveolar
spaces, where it can survive and replicate in the extracellular environment. This yeast has …
spaces, where it can survive and replicate in the extracellular environment. This yeast has …
Fbp1-mediated ubiquitin-proteasome pathway controls Cryptococcus neoformans virulence by regulating fungal intracellular growth in macrophages
TB Liu, C Xue - Infection and immunity, 2014 - Am Soc Microbiol
Cryptococcus neoformans is a human fungal pathogen that often causes lung and brain
infections in immunocompromised patients, with a high fatality rate. Our previous results …
infections in immunocompromised patients, with a high fatality rate. Our previous results …
The outcome of the Cryptococcus neoformans–macrophage interaction depends on phagolysosomal membrane integrity
D Leon-Rodriguez, M Carlos, DCP Rossi… - The Journal of …, 2018 - journals.aai.org
Cryptococcus neoformans is a fungal pathogen with worldwide distribution. C. neoformans
resides within mature phagolysosomes where it often evades killing and replicates. C …
resides within mature phagolysosomes where it often evades killing and replicates. C …
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