[HTML][HTML] C3 glomerulopathy: consensus report

MC Pickering, VD D'agati, CM Nester, RJ Smith… - Kidney international, 2013 - Elsevier
C3 glomerulopathy is a recently introduced pathological entity whose original definition was
glomerular pathology characterized by C3 accumulation with absent or scanty …

Update on C3 glomerulopathy: a complement-mediated disease

F Caravaca-Fontán, L Lucientes, T Cavero, M Praga - Nephron, 2020 - karger.com
Abstract C3 glomerulopathy (C3G) is a clinicopathologic entity secondary to dysregulation of
the alternative complement pathway in plasma and the glomerular microenvironment. The …

C3 glomerulopathy: ten years' experience at Mayo Clinic

A Ravindran, FC Fervenza, RJH Smith… - Mayo Clinic …, 2018 - Elsevier
Objective To describe the clinicopathological features, complement abnormalities, triggers,
treatment, and outcomes of C3 glomerulopathy. Patients and Methods A total of 114 patients …

C3 glomerulopathy—understanding a rare complement-driven renal disease

RJH Smith, GB Appel, AM Blom, HT Cook… - Nature reviews …, 2019 - nature.com
The C3 glomerulopathies are a group of rare kidney diseases characterized by complement
dysregulation occurring in the fluid phase and in the glomerular microenvironment, which …

C3 glomerulopathy: understanding an ultra‐rare complement‐mediated renal disease

AK Heiderscheit, JJ Hauer… - American Journal of …, 2022 - Wiley Online Library
Abstract C3 glomerulopathy (C3G) describes a pathologic pattern of injury diagnosed by
renal biopsy. It is characterized by the dominant deposition of the third component of …

Kidney transplantation in C3 glomerulopathy: a case series

R Regunathan-Shenk, RS Avasare, W Ahn… - American Journal of …, 2019 - Elsevier
Rationale & Objective C3 glomerulopathy (C3G), a form of glomerulonephritis associated
with dysregulation of the alternative complement pathway, occurs either as dense deposit …

Update on C3 glomerulopathy

TD Barbour, MM Ruseva… - Nephrology Dialysis …, 2016 - academic.oup.com
C3 glomerulopathy refers to a disease process in which abnormal control of complement
activation, degradation or deposition results in predominant C3 fragment deposition within …

[HTML][HTML] C3 glomerulonephritis: clinicopathological findings, complement abnormalities, glomerular proteomic profile, treatment, and follow-up

S Sethi, FC Fervenza, Y Zhang, L Zand, JA Vrana… - Kidney international, 2012 - Elsevier
C3 glomerulonephritis (C3GN) is a recently described disorder that typically results from
abnormalities in the alternative pathway (AP) of complement. Here, we describe the clinical …

A narrative review on C3 glomerulopathy: A rare renal disease

FP Schena, P Esposito, M Rossini - International journal of molecular …, 2020 - mdpi.com
In April 2012, a group of nephrologists organized a consensus conference in Cambridge
(UK) on type II membranoproliferative glomerulonephritis and decided to use a new …

The role of complement in C3 glomerulopathy

PF Zipfel, C Skerka, Q Chen, T Wiech, T Goodship… - Molecular …, 2015 - Elsevier
C3 glomerulopathy describes a spectrum of disorders with glomerular pathology associated
with C3 cleavage product deposition and with defective complement action and regulation …