Epilepsy is a network disorder driven by fundamental changes in the function of the cells
which compose these networks. Driving this aberrant cellular function are large scale …

Epigenetic mechanisms are regulatory processes that control gene expression changes
involved in multiple aspects of neuronal function, including central nervous system …

Epigenetic processes in the brain involve the transfer of information arising from short-lived
cellular signals and changes in neuronal activity into lasting effects on gene expression. Key …

Epilepsy is a common and devastating neurological disorder characterized by recurrent and
unprovoked spontaneous seizures. One leading hypothesis for the development and …

The rapidly emerging science of epigenetics and epigenomic medicine promises to reveal
novel insights into the susceptibility to and the onset and progression of epileptic disorders …

Epigenetics refers broadly to processes that influence medium to long‐term gene
expression by changing the readability and accessibility of the genetic code. The …

This article highlights the emerging therapeutic potential of specific epigenetic modulators
as promising antiepileptogenic or disease-modifying agents for curing epilepsy. Currently …

In humans, genomic DNA is organized in 23 chromosome pairs coding for roughly 25,000
genes. Not all of them are active at all times. During development, a broad range of different …

Epilepsy affects over 50 million individuals globally, making it the most prevalent chronic
and serious neurological condition. A precise therapeutic strategy is complicated by poor …

The rapid technical progress made in molecular genetics has provided new strategies to
study the molecular pathogenesis of human epilepsy. In particular, the abilities to assay the …