Cryptococcus neoformans, an encapsulated basidiomycete fungus of medical importance, is
capable of crossing the blood-brain barrier and causing meningitis in both …

The acquisition of iron from mammalian hosts is an important aspect of infection because
microbes must compete with the host for this nutrient and iron perception often regulates …

Cryptococcus neoformans is an encapsulated yeast-like fungus of worldwide distribution.
Melanin production is an important virulence factor of C. neoformans. We report the …

The opportunistic fungal pathogen Cryptococcus neoformans is a leading cause of mortality
among the human immunodeficiency virus/acquired immunodeficiency syndrome …

Melanin is an antioxidant polyphenol pigment required for the pathogenicity of many fungal
pathogens, but comprehensive regulatory mechanisms remain unidentified. In this study, we …

In the present paper, we investigated the involvement of cryptococcal melanogenesis and
macrophage nitric oxide (NO) production in the accomplishment of anticryptococcal activity …

Laccases are thought to be important to the virulence of many fungal pathogens by
producing melanin, a presumed oxygen radical scavenger. A laccase in Cryptococcus …

A hallmark feature of several pathogenic microbes is the distinctive color of their colonies
when propagated in the clinical laboratory. Such pigmentation comes in a variety of hues …

While laccase of Cryptococcus neoformans is implicated in the virulence of the organism,
our recent studies showing absence of melanin in the infected mouse brain has led us to a …

The fungus Cryptococcus neoformans is an opportunistic human pathogen that causes a life-
threatening meningoencephalitis by expression of virulence factors such as melanin, a black …