Melanisation of Cryptococcus neoformans in human brain tissue

JD Nosanchuk, AL Rosas, SC Lee, A Casadevall - The Lancet, 2000 - thelancet.com
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Cryptococcus neoformans and Cryptococcus gattii, the etiologic agents of cryptococcosis

KJ Kwon-Chung, JA Fraser… - Cold Spring …, 2014 - perspectivesinmedicine.cshlp.org
Cryptococcus neoformans and Cryptococcus gattii are the two etiologic agents of
cryptococcosis. They belong to the phylum Basidiomycota and can be readily distinguished …

Cryptococcus neoformans Gene Expression during Experimental Cryptococcal Meningitis

BR Steen, S Zuyderduyn, DL Toffaletti, M Marra… - Eukaryotic …, 2003 - Am Soc Microbiol
Cryptococcus neoformans, an encapsulated basidiomycete fungus of medical importance, is
capable of crossing the blood-brain barrier and causing meningitis in both …

Iron and fungal pathogenesis: a case study with Cryptococcus neoformans

WH Jung, JW Kronstad - Cellular microbiology, 2008 - Wiley Online Library
The acquisition of iron from mammalian hosts is an important aspect of infection because
microbes must compete with the host for this nutrient and iron perception often regulates …

Dual Infections with Pigmented and Albino Strains of Cryptococcus neoformans in Patients with or without Human Immunodeficiency Virus Infection in India

P Mandal, U Banerjee, A Casadevall… - Journal of clinical …, 2005 - Am Soc Microbiol
Cryptococcus neoformans is an encapsulated yeast-like fungus of worldwide distribution.
Melanin production is an important virulence factor of C. neoformans. We report the …

Comparative Genomics of Serial Isolates of Cryptococcus neoformans Reveals Gene Associated With Carbon Utilization and Virulence

KL Ormerod, CA Morrow, EWL Chow… - G3: Genes …, 2013 - academic.oup.com
The opportunistic fungal pathogen Cryptococcus neoformans is a leading cause of mortality
among the human immunodeficiency virus/acquired immunodeficiency syndrome …

Distinct Stress Responses of Two Functional Laccases in Cryptococcus neoformans Are Revealed in the Absence of the Thiol-Specific Antioxidant Tsa1

TA Missall, JM Moran, JA Corbett, JK Lodge - Eukaryotic Cell, 2005 - Am Soc Microbiol
Laccases are thought to be important to the virulence of many fungal pathogens by
producing melanin, a presumed oxygen radical scavenger. A laccase in Cryptococcus …

Role of nitric oxide and melanogenesis in the accomplishment of anticryptococcal activity by the BV-2 microglial cell line

E Blasi, R Barluzzi, R Mazzolla, B Tancini… - Journal of …, 1995 - Elsevier
In the present paper, we investigated the involvement of cryptococcal melanogenesis and
macrophage nitric oxide (NO) production in the accomplishment of anticryptococcal activity …

Color me bad: microbial pigments as virulence factors

GY Liu, V Nizet - Trends in microbiology, 2009 - cell.com
A hallmark feature of several pathogenic microbes is the distinctive color of their colonies
when propagated in the clinical laboratory. Such pigmentation comes in a variety of hues …

Regulation of melanin production by Cryptococcus neoformans

TA Nurudeen, DG Ahearn - Journal of clinical Microbiology, 1979 - Am Soc Microbiol
Species of Filobasidiella, the agents of cryptococcosis, produced melanin-like pigments
within 4 to 48 h with diphenol, aminophenol, and diaminobenzene compounds as …