This study examines the atrophy patterns in the entorhinal and transentorhinal cortices of
subjects that converted from normal cognition to mild cognitive impairment. The regions …

Introduction Autopsy findings have shown the entorhinal cortex and transentorhinal cortex
are among the earliest sites of accumulation of pathology in patients developing Alzheimer's …

Background The most characteristic symptom of Alzheimer's disease (AD) is episodic
memory impairment, which is closely associated with atrophy of the entorhinal cortex …

This study examines the atrophy rates of subjects with mild cognitive impairment (MCI)
compared to controls in four regions within the medial temporal lobe: the transentorhinal …

BACKGROUND AND PURPOSE: The entorhinal cortex, a critical gateway between the
neocortex and hippocampus, is one of the earliest regions affected by Alzheimer disease …

Background: Magnetic resonance imaging (MRI) of hippocampal atrophy is a sensitive but
not specific method to support the clinical diagnosis of early Alzheimer's disease (AD). We …

Using quantitative structural MRI protocols, we examined the effects of age on alterations in
entorhinal cortex (EC) volume. The left EC was found to be smaller than the right in both …

To examine the biological basis of subjective memory impairment (SMI), defined as the
feeling of memory worsening with normal memory performance, we measured the volume of …

Neuroimaging studies have routinely used hippocampal volume as a measure of
Alzheimer's disease severity, but hippocampal changes occur too late in the disease …

Aims In order to confirm the utility of the voxel‐based specific regional analysis system for A
lzheimer's disease (VSRAD) in assessing the atrophy of the entorhinal cortex, we …