Cocaine addiction is a complex and multifaceted process encompassing a number of forms
of behavioral plasticity. The process of acquiring and consuming drugs can be sufficiently …

Conditioned environmental stimuli are known to be important determinants of drug seeking.
Traditional models of drug seeking under the control of conditioned stimuli have focused on …

Rationale. The relative reinforcing strength of cocaine can be characterized by the
distribution of operant behavior during the availability of other reinforcing stimuli. Objective …

The concept of compulsive cocaine-seeking habits is difficult to reconcile with other
evidence showing that humans and even rats remain able to shift their choice away from the …

Drug-associated cues have profound effects on an addict's emotional state and drug-
seeking behavior. Although this influence must involve the motivational neural system that …

Associative learning is essential for establishing appropriate responses to cause–effect
relationships and effective behavioral adjustments to environmental changes. However …

Rationale Addiction is characterized by intermittent drug seeking despite rising costs. This
behavior is heavily influenced by environmental stimuli that signal drug availability and …

Cocaine addiction is characterized by long-lasting vulnerability to relapse arising because
neutral environmental stimuli become associated with drug use and then act as cues that …

The process of addiction in humans involves a transition from recreational drug use to
compulsive drug-taking. To understand or study this behavioral phenomenon from a …

Abstract In 1993, Robinson and Berridge published their first review that laid out the
incentive sensitization theory of addiction (Robinson and Berridge 1993 Brain Res Rev 18 …