Application of HaloTag® Technology to in Vivo Molecular Imaging Using Protein Probes Labeled by Metallic Radionuclides

S Kimura, Y Kakishima, T Kuchimaru… - …, 2016 - jstage.jst.go.jp
We are developing new protein probes for in vivo radionuclide imaging using HaloTag®
interchangeable labeling system. The selective and rapid bond formation between the …

Dual-modality HaloTag ligands for SPECT/CT and optical imaging

J Knight, M Stratford, S Faulkner, HT Uyeda, M Cong… - 2014 - Soc Nuclear Med
1060 Objectives HaloTag® technology is based on the rapid and highly selective formation
of a covalent bond between HaloTag protein and a chloroalkane HaloTag ligand. The ability …

Labelling HaloTag fusion proteins with HaloTag ligand in living cells

HN Duc, X Ren - Bio-protocol, 2017 - bio-protocol.org
www.bio-protocol.org/e2526 Labelling HaloTag Fusion Proteins with HaloTag Ligand in
Living Cells Huy Nguyen Duc and Xiaojun Ren* Page 1 www.bio-protocol.org/e2526 Vol 7 …

HaloTag technology for specific and covalent labeling of fusion proteins

HA Benink, M Urh - Site-Specific Protein Labeling: Methods and Protocols, 2015 - Springer
Appending proteins of interest to fluorescent protein tags such as GFP has revolutionized
how proteins are studied in the cellular environment. Over the last few decades many …

The HaloTag™: a novel technology for cell imaging and protein analysis

GV Los, K Wood - High Content Screening: A Powerful Approach to …, 2006 - Springer
The ability to specifically label proteins with a wide range of optical properties and
functionalities can help reveal information about protein functions and dynamics in living …

[HTML][HTML] Recent biomedical advances enabled by HaloTag technology

C Weiyu, MH Younis, Z Zhongkuo… - Biocell: official journal of …, 2022 - ncbi.nlm.nih.gov
The knowledge of interactions among functional proteins helps researchers understand
disease mechanisms and design potential strategies for treatment. As a general approach …

HaloTag technology: a versatile platform for biomedical applications

CG England, H Luo, W Cai - Bioconjugate chemistry, 2015 - ACS Publications
Exploration of protein function and interaction is critical for discovering links among
genomics, proteomics, and disease state; yet, the immense complexity of proteomics found …

[HTML][HTML] HaloTag as a reporter gene: positron emission tomography imaging with 64Cu-labeled second generation HaloTag ligands

H Hong, HA Benink, HT Uyeda… - American Journal of …, 2013 - ncbi.nlm.nih.gov
The goal of this study is to employ the HaloTag technology for positron emission tomography
(PET), which involves two components: the HaloTag protein (a modified hydrolase which …

HaloTag as a reporter gene for PET

H Hong, H Benink, HT Uyeda, Y Zhang, T Barnhart… - 2013 - Soc Nuclear Med
1092 Objectives To employ HaloTag technology for positron emission tomography (PET),
which involves 2 components: HaloTag protein (an engineered haloalkane dehalogenase …

[HTML][HTML] HaloTag: a novel reporter gene for positron emission tomography

H Hong, HA Benink, Y Zhang, Y Yang… - American journal of …, 2011 - ncbi.nlm.nih.gov
Among the many molecular imaging techniques, reporter gene imaging has been a dynamic
area of research. The HaloTag protein is a modified haloalkane dehalogenase which was …