Opinion statement When possible, surgical resection remains the “gold standard” for the
treatment of hepatic colorectal metastases. Liver resection should be considered when …

Options for Second-Line Treatment in Metastatic Colorectal Cancer Page 1 46 Clinical
Advances in Hematology & Oncology Volume 14, Issue 1 January 2016 Options for Second-Line …

Colorectal cancer patients with isolated liver metastasis are potentially cured with surgical
resection. Recent advances in systemic chemotherapy have increased the ability to convert …

A proliferation of new cytotoxic and biologic agents has led to improved survival in patients
with metastatic colorectal cancer (mCRC). The ability of surgery to increase long‐term …

Background Patients with metastatic colorectal cancer (mCRC) often have other medical
conditions that may impact treatment decisions, prognoses and quality of care. We aimed to …

Irinotecan-based second-line chemotherapy of metastatic colorectal cancer (CRC) is
effective, it might, however, be contraindicated in cases of severe liver dysfunction due to …

Abstract Learning Objectives After completing this course, the reader will be able to:
Describe the evolution of cancer chemotherapy for patients with colorectal cancer. Discuss …

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Introduction: The liver is the most common metastatic site in colorectal cancer with more than
half the patients developing a liver metastasis either at the time of their diagnosis …

Recently, in patients with unresectable colorectal liver metastasis, liver resection sometimes
becomes possible by intensive systemic chemotherapy, ie conversion therapy. However …