Is resection of colorectal liver metastases after a second‐line chemotherapy regimen justified?
BACKGROUND: Patient outcomes following resection of colorectal liver metastases (CLM)
after second‐line chemotherapy regimen is unknown. METHODS: From August 1998 to …
after second‐line chemotherapy regimen is unknown. METHODS: From August 1998 to …
Metastatic colorectal cancer: Current treatment and future options for improved survival Medical approach – present status
B Glimelius, N Cavalli-Björkman - Scandinavian journal of …, 2012 - Taylor & Francis
Background. Metastatic colorectal cancer has a poor prognosis, and the majority of patients
are left with palliative measures. The development seen using medical treatments are …
are left with palliative measures. The development seen using medical treatments are …
Should the results of the new EPOC trial change practice in the management of patients with resectable metastatic colorectal cancer confined to the liver?
B Nordlinger, GJ Poston, RM Goldberg - Journal of Clinical Oncology, 2015 - ascopubs.org
Biologic agents, specifically epidermal growth factor receptor blockers and vascular
endothelial growth factor inhibitors, combined with cytotoxic agents have become a standard …
endothelial growth factor inhibitors, combined with cytotoxic agents have become a standard …
Clinical practice patterns in chemotherapeutic treatment regimens for metastatic colorectal cancer
J McLean, YS Rho, G Kuruba, A Mamo, M Gilabert… - Clinical colorectal …, 2016 - Elsevier
Background The treatment of patients with metastatic colorectal cancer (mCRC) has evolved
during the past 2 decades, and patient survival has increased. Consequently, patients are …
during the past 2 decades, and patient survival has increased. Consequently, patients are …
[HTML][HTML] Improvement in survival of metastatic colorectal cancer: are the benefits of clinical trials reproduced in population-based studies?
Abstract Aim of the Study To describe trends in survival of non-resectable metastatic
colorectal cancer (MCRC) over a 34-year period in a French population-based registry …
colorectal cancer (MCRC) over a 34-year period in a French population-based registry …
Does chemotherapy prior to liver resection increase the potential for cure in patients with metastatic colorectal cancer? A report from the European Colorectal …
B Nordlinger, E Van Cutsem, P Rougier… - European journal of …, 2007 - Elsevier
Liver resection offers the only chance of cure for patients with advanced colorectal cancer
(CRC). Typically, the 5-year survival rates following liver resection range from 25% to 40 …
(CRC). Typically, the 5-year survival rates following liver resection range from 25% to 40 …
Outcome of molecular targeted agents plus chemotherapy for second-line therapy of metastatic colorectal cancer: a meta-analysis of randomized trials
X Pei, Y Liu, L Sun, J Zhang, Y Fang, X Liao, J Liu… - Clinical colorectal …, 2016 - Elsevier
Introduction The aim of this study was to evaluate the efficacy and toxicity of molecular
targeted agents plus chemotherapy compared with chemotherapy alone as second-line …
targeted agents plus chemotherapy compared with chemotherapy alone as second-line …
Prognostic value of liver metastases in colorectal cancer treated by systemic therapy: An ARCAD pooled analysis.
3554 Background: Approximately 30% of patients (pts) diagnosed with colorectal cancer
(CRC) develop liver metastases (LM). Liver is the most common organ of metastasis of CRC …
(CRC) develop liver metastases (LM). Liver is the most common organ of metastasis of CRC …
Metastatic colorectal cancer: recent advances in its clinical management
ME Barugel, C Vargas… - Expert review of …, 2009 - Taylor & Francis
Colorectal cancer (CRC) is frequently complicated by metastatic disease, with the liver being
the most common site of metastasis. Surgical resection is the only realistic cure for colorectal …
the most common site of metastasis. Surgical resection is the only realistic cure for colorectal …
Metastatic colorectal cancer: role of target therapies and future perspectives.
A Nappi, M Berretta, C Romano, S Tafuto… - Current cancer drug …, 2018 - europepmc.org
Today, we are experiencing a real cultural revolution in the therapeutic approach to cancer
of the colon-rectum, that by orphan disease, it is now becoming an important paradigm of …
of the colon-rectum, that by orphan disease, it is now becoming an important paradigm of …