Docetaxel-loaded cholesterol-PEG co-modified poly (n-butyl) cyanoacrylate nanoparticles for antitumor drug pulmonary delivery: preparation, characterization, and in …

X Hu, F Yang, Y Liao, L Li, G Zhao… - International Journal of …, 2020 - Taylor & Francis
Background and Aim Polymeric nanoparticles (NPs) have received much attention as
promising carrier systems in lung cancer and brain metastases. Methods Here, for the first …

Preparation, optimization, and in vivo evaluation of nanoparticle-based formulation for pulmonary delivery of anticancer drug

N Chishti, S Jagwani, D Dhamecha, S Jalalpure… - Medicina, 2019 - mdpi.com
Background and Oobjectives: Lung cancer, a pressing issue in present-day society due to its
high prevalence and mortality rate, can be managed effectively by long-term delivery of …

Pulmonary delivery by exploiting doxorubicin and cisplatin co-loaded nanoparticles for metastatic lung cancer therapy

C Xu, Y Wang, Z Guo, J Chen, L Lin, J Wu… - Journal of controlled …, 2019 - Elsevier
Despite advances in cancer therapy, effective local treatment remains a formidable
challenge due to the limit of efficient drug delivery method and the toxicity of …

Paclitaxel and quercetin nanoparticles co-loaded in microspheres to prolong retention time for pulmonary drug delivery

K Liu, W Chen, T Yang, B Wen, D Ding… - International journal …, 2017 - Taylor & Francis
High drug resistance, poor water solubility, short half-life, and low local drug concentration
are obstacles for successful delivery of chemotherapeutic drugs for lung cancer. A new …

Nanoparticle delivery of chemotherapy combination regimen improves the therapeutic efficacy in mouse models of lung cancer

J Tian, Y Min, Z Rodgers, X Wan, H Qiu, Y Mi… - … , Biology and Medicine, 2017 - Elsevier
The combination chemotherapy regimen of cisplatin (CP) and docetaxel (DTX) is effective
against a variety of cancers. However, combination therapies present unique challenges …

Inhalable spray dried lipidnanoparticles for the co-delivery of paclitaxel and doxorubicin in lung cancer

P Kaur, V Mishra, T Shunmugaperumal… - Journal of Drug Delivery …, 2020 - Elsevier
The present study aimed to develop and evaluate inhalable nanocarriers using different
surfactants for enhancing the antitumor efficacy of chemotherapeutics. Surfactants …

Chondroitin sulphate decorated polymeric nanoparticles: An effective carrier for enhancement of lung cancer targeting capabilities of anticancer drug

S Garg, A Garg, S Enaganti… - … Formerly: Recent Patents …, 2019 - ingentaconnect.com
Background: Currently, cancer is rising as one of the dominant causes of human deaths
worldwide. The application of nano-carriers may help to treat cancer through the delivery of …

Paclitaxel-loaded poly(glycolide-co-ε-caprolactone)-b-D-α-tocopheryl polyethylene glycol 2000 succinate nanoparticles for lung cancer therapy

T Zhao, H Chen, Y Dong, J Zhang… - International journal …, 2013 - Taylor & Francis
In order to improve the therapeutic efficacy and minimize the side effects of lung cancer
chemotherapy, the formulation of paclitaxel-loaded poly (glycolide-co-ε-caprolactone)-bD-α …

Nanocarrier-Mediated Drug Delivery via Inhalational Route for Lung Cancer Therapy: A Systematic and Updated Review

N Ara, A Hafeez - AAPS PharmSciTech, 2024 - Springer
Lung cancer is one of the most severe lethal malignancies, with approximately 1.6 million
deaths every year. Lung cancer can be broadly categorised into small and non-small-cell …

Docetaxel-loaded biomimetic nanoparticles for targeted lung cancer therapy in vivo

C Chi, F Li, H Liu, S Feng, Y Zhang, D Zhou… - Journal of Nanoparticle …, 2019 - Springer
Although the nanodrug-loading system provides new ideas for the effective treatment of
cancer, the lack of active cancer targeting, easy to be cleared by the reticuloendothelial …