Delivery of CRISPR (clustered regularly interspaced short palindromic repeats)/CRISPR‐
associated protein‐9 (Cas9) represents a major hurdle for successful clinical translation of …

Recent advances in molecular biology have led to the CRISPR revolution, but the lack of an
efficient and safe delivery system into cells and tissues continues to hinder clinical …

The CRISPR-Cas9 system is a powerful gene-editing tool with wide-ranging applications,
but the safe and efficient intracellular delivery of CRISPR components remains a challenge …

A facile method was designed that can specifically deliver CRISPR/Cas9 into target cells
nuclei and reduce the off-target effects. A multifunctional delivery vector for FOXM1 knockout …

CRISPR–Cas9 is a revolutionary genome-editing technology that has enormous potential
for the treatment of genetic diseases. However, the lack of efficient and safe, non-viral …

Background The clustered regularly interspaced short palindromic repeats (CRISPR) and
Cas9 protein system is a revolutionary tool for gene therapy. Despite promising reports of …

CRISPR (clustered, regularly interspaced, short palindromic repeats)/CRISPR-associated
protein 9 (Cas9) system has emerged as a powerful genome-editing tool to correct genetic …

The-state-of-art CRISPR/Cas9 is one of the most powerful among the approaches being
developed to rescue fundamental causes of gene-based inheritable diseases. Several …

CRISPR was first observed in 1987 in bacteria and archaea and was later confirmed as part
of bacterial adaptive immunity against the attacking phage. The CRISPR/Cas restriction …

Clustered Regularly Interspaced Short Palindromic Repeats associated protein 9
(CRISPR/Cas9) has transformed our ability to edit the human genome selectively. This …