Combinatorial immunotherapy and nanoparticle mediated hyperthermia

AJ Moy, JW Tunnell - Advanced drug delivery reviews, 2017 - Elsevier
Immune checkpoint therapy has become the first widely adopted immunotherapy for patients
with late stage malignant melanoma, with potential for a wide range of cancers. While some …

Recent progress in the synergistic combination of nanoparticle‐mediated hyperthermia and immunotherapy for treatment of cancer

ZR Stephen, M Zhang - Advanced healthcare materials, 2021 - Wiley Online Library
Immunotherapy has demonstrated great clinical success in certain cancers, driven primarily
by immune checkpoint blockade and adoptive cell therapies. Immunotherapy can elicit …

[HTML][HTML] Hyperthermia targeting the tumor microenvironment facilitates immune checkpoint inhibitors

Z Li, J Deng, J Sun, Y Ma - Frontiers in Immunology, 2020 - frontiersin.org
Immune checkpoint inhibitors (ICIs) have ushered in a new era of cancer therapy; however,
ICIs are only effective in selective patients. The efficacy of ICIs is closely related to the tumor …

[HTML][HTML] Hyperthermia combined with immune checkpoint inhibitor therapy in the treatment of primary and metastatic tumors

X Yang, M Gao, R Xu, Y Tao, W Luo, B Wang… - Frontiers in …, 2022 - frontiersin.org
According to the difference in temperature, thermotherapy can be divided into thermal
ablation and mild hyperthermia. The main advantage of thermal ablation is that it can …

[HTML][HTML] Amplifying cancer treatment: advances in tumor immunotherapy and nanoparticle-based hyperthermia

Y Zhang, Z Li, Y Huang, B Zou, Y Xu - Frontiers in Immunology, 2023 - frontiersin.org
In the quest for cancer treatment modalities with greater effectiveness, the combination of
tumor immunotherapy and nanoparticle-based hyperthermia has emerged as a promising …

Photothermal therapies to improve immune checkpoint blockade for cancer

PB Balakrishnan, EE Sweeney… - International Journal …, 2020 - Taylor & Francis
Immune checkpoint blockade (ICB) comprising monoclonal antibodies (mAbs) against
immune 'checkpoints', such as CTLA-4 and the PD1/PDL1 axis have dramatically improved …

[HTML][HTML] Recent advancements in nanomedicine for 'cold'tumor immunotherapy

Q Chen, T Sun, C Jiang - Nano-micro letters, 2021 - Springer
Although current anticancer immunotherapies using immune checkpoint inhibitors (ICIs)
have been reported with a high clinical success rate, numerous patients still bear …

Hyperthermia combined with immune checkpoint inhibitor therapy: Synergistic sensitization and clinical outcomes

P Liu, M Ye, Y Wu, L Wu, K Lan, Z Wu - Cancer medicine, 2023 - Wiley Online Library
Background Within the field of oncotherapy, research interest regarding immunotherapy has
risen to the point that it is now seen as a key application. However, inherent disadvantages …

Thermal immuno-nanomedicine in cancer

Z Yang, D Gao, J Zhao, G Yang, M Guo… - Nature Reviews …, 2023 - nature.com
Immunotherapy has revolutionized the treatment of patients with cancer. However,
promoting antitumour immunity in patients with tumours that are resistant to these therapies …

Recent advances in hyperthermia therapy‐based synergistic immunotherapy

M Chang, Z Hou, M Wang, C Li, J Lin - Advanced Materials, 2021 - Wiley Online Library
The past decades have witnessed hyperthermia therapy (HTT) as an emerging strategy
against malignant tumors. Nanomaterial‐based photothermal therapy (PTT) and magnetic …