Although the nanodrug-loading system provides new ideas for the effective treatment of
cancer, the lack of active cancer targeting, easy to be cleared by the reticuloendothelial …

Dual-receptor targeted (DRT) nanoparticles which contain two distinct targeting agents may
exhibit higher cell selectivity, cellular uptake, and cytotoxicity toward cancer cells than single …

To investigate the antitumor effect, biodistribution and penetration in tumors of docetaxel
(DOC)-loaded polyethylene glycol–poly (caprolactone)(mPEG–PCL) nanoparticles on …

Small cell lung cancer (SCLC) is one of the most malignant cancers in the world and 5-year
survival rate has not been significantly improved with conventional chemotherapy. Targeting …

Nowadays, non-small cell lung cancer (NSCLC) is threatening the health of all mankind.
Although many progresses on treatment of lung cancer have been achieved in the past few …

Taxanes, microtubule stabilizing agents, are extensively used in the treatment of non-small
cell lung cancer (NSCLC). However, their clinical effectiveness remains restricted owing to …

The attachment of polyethylene glycol (PEG) increases the circulation time of drug-
containing nanoparticles; however, this also negatively affects cellular uptake. To overcome …

Purpose Non-small cell lung cancer (NSCLC) therapy faces the barriers including drug
resistance. A transferrin-functionalized protein-lipid hybrid nanoparticle (PLHN) was …

In this study a 3-factor, 3-level Box-Behnken design was used to prepare optimized
docetaxel (DTX) loaded pegylated poly lactide-co-glycolide (PEG-PLGA) Nanoparticles …

In the present study, we developed a novel type of reduction-sensitive nanoparticles (NPs)
for docetaxel (DTX) delivery based on cross-linked lipoic acid NPs (LANPs). The …