Frequency and genotype distribution of ABCB1 gene polymorphisms among Maharashtrian population of Central India
S Pramanik, ST Surendran, S Devi, K Krishnamurthi… - Xenobiotica, 2014 - Taylor & Francis
Apart from conferring multidrug resistance to cancer cells, P-glycoprotein (P-gp) encoded by
the gene ABCB1 (also, known as Multidrug resistance gene, MDR1), plays a major role in …
the gene ABCB1 (also, known as Multidrug resistance gene, MDR1), plays a major role in …
[引用][C] ABCB 1 gene expression in peripheral blood mononuclear cells in healthy Thai males and females
P Sudchada, S Oo-Puthinan, O Kerdpin, N Saelim - Genetics and Molecular Research, 2010
Promoter polymorphisms and allelic imbalance in ABCB1 expression
C Loeuillet, M Weale, S Deutsch, M Rotger… - Pharmacogenetics …, 2007 - journals.lww.com
Objective The ABCB1 (MDR1) gene, encoding the transporter P-glycoprotein, is known to
act on a broad range of prescription medicines. For this reason a large number of studies …
act on a broad range of prescription medicines. For this reason a large number of studies …
Distribution of ABCB1, CYP3A5, CYP2C19, and P2RY12 gene polymorphisms in a Mexican Mestizos population
G Vargas-Alarcón, J Ramírez-Bello, A de la Peña… - Molecular biology …, 2014 - Springer
The aim of the present study was to establish the gene frequency of six polymorphisms of
the ABCB1, CYP3A5, CYP2C19, and P2RY12 genes in a population resident of Mexico City …
the ABCB1, CYP3A5, CYP2C19, and P2RY12 genes in a population resident of Mexico City …
[HTML][HTML] Gene-Wide Characterization of Common Quantitative Trait Loci for ABCB1 mRNA Expression in Normal Liver Tissues in the Chinese Population
W Shou, D Wang, K Zhang, B Wang, Z Wang, J Shi… - 2012 - journals.plos.org
In order to comprehensively screen genetic variants leading to differential expression of the
important human ABCB1 gene in the primary drug-metabolizing organ, ABCB1 mRNA …
important human ABCB1 gene in the primary drug-metabolizing organ, ABCB1 mRNA …
An update on ABCB1 pharmacogenetics: insights from a 3D model into the location and evolutionary conservation of residues corresponding to SNPs associated with …
SJ Wolf, M Bachtiar, J Wang, TS Sim… - The …, 2011 - nature.com
The human ABCB1 protein,(P-glycoprotein or MDR1) is a membrane-bound glycoprotein
that harnesses the energy of ATP hydrolysis to drive the unidirectional transport of …
that harnesses the energy of ATP hydrolysis to drive the unidirectional transport of …
Association of ABCB1 gene polymorphisms with plasma lipid and apolipoprotein concentrations in the STANISLAS cohort
E Jeannesson, G Siest, B Bastien, L Albertini… - Clinica chimica acta, 2009 - Elsevier
BACKGROUND: While involvement of ABCB1 is well known in drug transport, its metabolite
transport role is not so well understood. Like other ABC transporters, ABCB1 might be …
transport role is not so well understood. Like other ABC transporters, ABCB1 might be …
Strong linkage disequilibrium at the nucleotide analogue transporter ABCC5 gene locus
PC Gwee, K Tang, PH Sew, EJD Lee… - Pharmacogenetics …, 2005 - journals.lww.com
The ABCC5 transporter is a ubiquitously expressed ATP-dependent efflux pump that exports
nucleotide analogues, including thiopurine anticancer drugs and antiviral drugs …
nucleotide analogues, including thiopurine anticancer drugs and antiviral drugs …
Functional evaluation of polymorphisms in the human ABCB1 gene and the impact on clinical responses of antiepileptic drugs
CC Hung, CC Chen, CJ Lin… - Pharmacogenetics and …, 2008 - journals.lww.com
Objective The ABCB1 haplotype combinations have been demonstrated to be associated
with epilepsy treatment outcomes. The aim of this study is to investigate whether ABCB1 …
with epilepsy treatment outcomes. The aim of this study is to investigate whether ABCB1 …
Biological and genetic factors associated with ABCB1 and pregnane-X-receptor expressions in peripheral blood mononuclear cells in the STANISLAS cohort
E Jeannesson, G Siest, B Herbeth, L Albertini… - 2011 - degruyter.com
Background: ABCB1 is a membrane transporter ubiquitously expressed particularly in
peripheral blood mononuclear cells (PBMCs). Resistance to drugs is associated with …
peripheral blood mononuclear cells (PBMCs). Resistance to drugs is associated with …