Abstract Background/Aim The number of patients receiving amiodarone will increase in
future years. As clinically significant hepatotoxicity associated with oral amiodarone is …

Potential hepatotoxicity related to amiodarone therapy is often a concern when deciding
whether to initiate or continue treatment with this medication. While mostly associated with …

Drug and Chemical Toxicology and males showed a higher incidence of hepatotoxicity than
females in patients receiving iv amiodarone treatment (Huang et al., 2009). Hepatic toxicity …

Background Amiodarone causes hepatotoxicity in experimental models, but in humans, the
relationships between drug administration, serum concentrations, markers of liver function …

Background Liver cirrhosis is an uncommon but not rare side effect of amiodarone-induced
hepatotoxicity. Patients with hepatitis B virus and hepatitis C virus infections are at a high …

Risk factors and underlying mechanisms for liver injury associated with amiodarone remain
elusive. This study aimed to investigate the drug-related covariates for acute liver injury by …

The prevalence of apparent amiodarone-related hepatic injury in 104 patients followed
prospectively is compared to that reported in the literature. Asymptomatic elevation of serum …

Background Intravenous (IV) amiodarone may be associated with liver injury that may
necessitate drug discontinuation. The prediction of amiodarone induced liver injury (AILI) …

Discussion Amiodarone is a commonly used antiarrhythmic. It is associated with
extracardiac side effects, including asymptomatic hepatic dysfunction in 15–40% of patients …

Abstract Background and Aims: Hepatotoxic complications of long-term oral amiodarone
therapy have been well described; however, liver injury secondary to parenteral infusion of …