Incorporation of heterocycles into drug molecules can enhance physical properties and
biological activity. A variety of heterocyclic groups is available to medicinal chemists, many …

Since the synthesis of 4, 6-dinitrobenzofuroxan in 1899 by Drost, benzofuroxans have
attracted particular attention. This peculiar series of compounds exhibit a broad spectrum of …

O‐Heterocycles have been explored in the field of medicinal chemistry for a long time, but
their significance has not been duly recognised and they are often shunned in favour of N …

The five-membered aromatic heterocycles containing oxygen and sulfur are key building
blocks used in medicinal chemistry applications. Furans, thiophenes and related azole …

Abstract The uses of 1, 2, 4-oxadiazoles include those as agonists at muscarinic receptors, 5-
hydroxytryptamine (5-HT) receptor antagonists, benzodiazepine receptor agonists, potent …

Oxadiazoles are five-membered heteroaromatic rings containing two carbons, two nitrogens,
and one oxygen atom, and they exist in different regioisomeric forms. Oxadiazoles are …

1. Introduction The first preparation of a furazan (1, 2, 5-oxadiazole) fused to a five
membered carbocyclic ring was published 90 years ago [1]. A furazan fused to a five …

As we know that, Oxadiazole or furadi azole ring containing derivatives are an important
class of heterocyclic compounds. A heterocyclic five-membered ring that possesses two …

The chemistry of furoxans (1, 2, 5-oxadiazole-2-oxides) and benzofuroxans (benzo [1, 2-c] 1,
2, 5-oxadiazole-1-oxides) is very well known. These systems are widely used in organic …

Background: Pyrazole is one of the excellent structural motifs in medicinal chemistry.
Various physiological and therapeutic possibilities have been exploited by incorporating …