[HTML][HTML] Reduced pathogenicity of the SARS-CoV-2 omicron variant in hamsters

K McMahan, V Giffin, LH Tostanoski, B Chung… - Med, 2022 - cell.com
Background The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron
(B. 1.1. 529) variant has proven to be highly transmissible and has outcompeted the Delta …

[HTML][HTML] Pathogenicity of SARS-CoV-2 Omicron (R346K) variant in Syrian hamsters and its cross-neutralization with different variants of concern

S Mohandas, PD Yadav, G Sapkal, AM Shete… - …, 2022 - thelancet.com
Summary Background SARS-CoV-2 Omicron variant is rampantly spreading across the
globe. We assessed the pathogenicity and immune response generated by BA. 1.1 sub …

[HTML][HTML] Attenuated replication and pathogenicity of SARS-CoV-2 B. 1.1. 529 Omicron

H Shuai, JFW Chan, B Hu, Y Chai, TTT Yuen, F Yin… - Nature, 2022 - nature.com
Abstract The Omicron (B. 1.1. 529) variant of SARS-CoV-2 emerged in November 2021 and
is rapidly spreading among the human population. Although recent reports reveal that the …

[HTML][HTML] SARS-CoV-2 Omicron variant causes mild pathology in the upper and lower respiratory tract of hamsters

F Armando, G Beythien, FK Kaiser, L Allnoch… - Nature …, 2022 - nature.com
Since its discovery in 2019, multiple variants of severe acute respiratory syndrome
coronavirus-2 (SARS-CoV-2) have been identified. This study investigates virus spread and …

[HTML][HTML] The omicron (B. 1.1. 529) SARS-CoV-2 variant of concern does not readily infect Syrian hamsters

R Abdelnabi, CS Foo, X Zhang, V Lemmens, P Maes… - Antiviral research, 2022 - Elsevier
The emergence of SARS-CoV-2 variants of concern (VoCs) has exacerbated the COVID-19
pandemic. End of November 2021, a new SARS-CoV-2 variant namely the omicron (B. 1.1 …

Omicron variant of SARS-CoV-2 imposes a new challenge for the global public health

Z Xu, K Liu, FG George - Biosafety and Health, 2022 - mednexus.org
Since its first discovery, the Omicron variant of severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) has evoked another wave of infection and caused global …

[HTML][HTML] Different pathogenesis of SARS-CoV-2 Omicron variant in wild-type laboratory mice and hamsters

YN Zhang, ZR Zhang, HQ Zhang, N Li… - … and Targeted Therapy, 2022 - nature.com
The COVID-19 pandemic caused by severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2) continues to disrupt global public health since its first report in December …

SARS-CoV-2 Omicron BA. 1 and BA. 2 are attenuated in rhesus macaques as compared to Delta

N van Doremalen, M Singh, TA Saturday, CK Yinda… - Science …, 2022 - science.org
Since the emergence of SARS-CoV-2, five different variants of concern (VOCs) have been
identified: Alpha, Beta, Gamma, Delta, and Omicron. Because of confounding factors in the …

Pathogenicity, transmissibility, and fitness of SARS-CoV-2 Omicron in Syrian hamsters

S Yuan, ZW Ye, R Liang, K Tang, AJ Zhang, G Lu… - Science, 2022 - science.org
The in vivo pathogenicity, transmissibility, and fitness of the severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2) Omicron (B. 1.1. 529) variant are not well …

[HTML][HTML] The viral fitness and intrinsic pathogenicity of dominant SARS-CoV-2 Omicron sublineages BA. 1, BA. 2, and BA. 5

H Shuai, JFW Chan, B Hu, Y Chai, C Yoon, H Liu… - …, 2023 - thelancet.com
Summary Background Among the Omicron sublineages that have emerged, BA. 1, BA. 2,
BA. 5, and their related sublineages have resulted in the largest number of infections. While …