Salvianolic acid B improves myocardial function in diabetic cardiomyopathy by suppressing IGFBP3

C Li, B Liu, Z Wang, F Xie, W Qiao, J Cheng… - Journal of molecular and …, 2020 - Elsevier
Abstract Background Salvianolic acid B (Sal B) is the representative component of phenolic
acids derived from the dried root and rhizome of Salvia miltiorrhiza Bge.(Labiatae), which …

[HTML][HTML] Salvianolic acid B-alleviated angiotensin II induces cardiac fibrosis by suppressing NF-κB pathway in vitro

C Wang, H Luo, Y Xu, L Tao, C Chang… - Medical science monitor …, 2018 - ncbi.nlm.nih.gov
Background Salvianolic acid B (SalB) is the representative component of phenolic acids
derived from the roots and rhizomes of Salvia miltiorrhiza Bge (Labiatae), which has been …

[HTML][HTML] Salvianolic acid A alleviates heart failure with preserved ejection fraction via regulating TLR/Myd88/TRAF/NF-κB and p38MAPK/CREB signaling pathways

A Dawuti, S Sun, R Wang, D Gong, R Liu… - Biomedicine & …, 2023 - Elsevier
Heart failure with preserved ejection fraction (HFpEF) is a morbid, fatal, and common
syndrome for which lack of evidence-based therapies. Salvianolic acid A (SAA), a major …

Salvianolic acid B alleviates diabetic endothelial and mitochondrial dysfunction by down-regulating apoptosis and mitophagy of endothelial cells

J Xiang, C Zhang, T Di, L Chen, W Zhao, L Wei… - …, 2022 - Taylor & Francis
Endothelial dysfunction is a critical mediator in the pathogenesis of vascular complications
of diabetes. Herein, this study was conducted to investigate the therapeutic effects of …

Salvianolic acid B improves vascular endothelial function in diabetic rats with blood glucose fluctuations via suppression of endothelial cell apoptosis

Y Ren, S Tao, S Zheng, M Zhao, Y Zhu, J Yang… - European Journal of …, 2016 - Elsevier
Vascular endothelial cell injury is an initial event in atherosclerosis. Salvianolic acid B (Sal
B), a main bioactive component in the root of Salvia miltiorrhiza, has vascular protective …

Salvianolic acid exerts cardioprotection through promoting angiogenesis in animal models of acute myocardial infarction: preclinical evidence

L Yu, KJ Zhang, JZ Zhu, Q Zheng… - Oxidative Medicine …, 2017 - Wiley Online Library
Radix Salviae miltiorrhizae, danshen root (danshen), is one of the widely used Chinese
herbal medicines in clinics, containing rich phenolic compounds. Salvianolic acid is the …

[HTML][HTML] Salvianolate reduces atrial fibrillation through suppressing atrial interstitial fibrosis by inhibiting TGF-β1/Smad2/3 and TXNIP/NLRP3 inflammasome signaling …

H Qiu, W Liu, T Lan, W Pan, X Chen, H Wu, D Xu - Phytomedicine, 2018 - Elsevier
Background Salvianolate is the main water-soluble bioactive compound of Salvia
Miltiorrhiza Bunge and is now clinically used in the treatment of cardiovascular diseases in …

[HTML][HTML] Salvianolic acid B functioned as a competitive inhibitor of matrix metalloproteinase-9 and efficiently prevented cardiac remodeling

B Jiang, J Chen, L Xu, Z Gao, Y Deng, Y Wang, F Xu… - BMC …, 2010 - Springer
Background Infarct-induced left ventricular (LV) remodeling is a deleterious consequence
after acute myocardial infarction (MI) which may further advance to congestive heart failure …

The effect of salvianolic acid on vascular protection and possible mechanisms

Y Wu, S Xu, XY Tian - Oxidative Medicine and Cellular …, 2020 - Wiley Online Library
Salvia miltiorrhiza (Danshen), as an important traditional Chinese medicinal plant, has been
used in China for the treatment of cardiovascular diseases for hundreds of years. Salvianolic …

[HTML][HTML] Salvianolic acid B ameliorates hyperglycemia and dyslipidemia in db/db mice through the AMPK pathway

MQ Huang, CJ Zhou, YP Zhang, XQ Zhang… - Cellular Physiology and …, 2016 - karger.com
Background/Aims: Salvianolic acid B (Sal B), a major polyphenolic compound of Salvia
miltiorrhiza Bunge, has been shown to possess potential antidiabetic activities. However, the …