The dysfunction of homologous and/or heterologous gap junctional intercellular
communication (GJIC) has been implicated in tumorigenesis of many kinds of cells. Here we …

The expression, localization, and function of connexins, the protein subunits that comprise
gap junctions, are often altered in cancer. In addition to cell–cell coupling through gap …

The objective of this study was to isolate and partially characterize several rat liver epithelial
cell clones containing myc, ras and myc/ras oncogenes in order to study their roles in …

Gap junction intercellular communication (GJIC) is involved in the regulation of many
cellular processes. The gap junction channels are made up of connexins and the flow of …

The normal development and health of all multicellular organisms, including the human
being, depend on the adaptive maintenance of the integrity of the genetic information (eg …

Among the several different forms of cell interactions known to exist in multicellular
organisms intercellular communication provides the most direct form of communication by …

Connexins and gap junctions play a crucial role during carcinogenesis. While diverse
regulatory systems have been shown to modulate their function, the influence of cell motility …

Gap junctional intercellular communication (GJIC) maintains normal growth and
differentiation of cells in a tissue. The intercellular molecules traversing gap junctions are …

Gap junctions (GJs) in astrocytes and glioma cells are important channels for cell-to-cell
communication that contribute to homo-and heterocellular coupling. According to recent …

Simple Summary Different connexins play diverse roles in cancers, either tumor-
suppressing or tumor-promoting. In lung cancer, Cx43 serves as a tumor suppressor at the …