A key challenge of central nervous system tumor surgery is to discriminate between brain
regions infiltrated by tumor cells and surrounding healthy tissue. Although monitoring of …

During glioblastoma surgery, delineation of the brain tumor margins is difficult because the
infiltrated and normal tissues have the same visual appearance. We use a fiber-optical …

We report the development of a compact point-detection fluorescence spectroscopy system
and two data analysis methods to quantify the intrinsic fluorescence redox ratio and …

Delineating tumor margins as accurately as possible is of primordial importance in surgical
oncology: extent of resection is associated with survival but respect of healthy surrounding …

The primary therapeutic approach for high-grade brain tumor is surgical resection. However,
identifying tumor margins in vivo remains a major challenge. Biopsy analysis remains the …

To complement a project towards the development of real-time optical biopsy for brain tissue
discrimination and surgical resection guidance, the optical properties of various brain …

Objective: The role of autofluorescence spectroscopy in the detection and staging of benign
and malignant brain tumors is being investigated in this study, with an additional aim of …

In the surgical treatment of malignant tumors, it is crucial to characterize the tumor as
precisely as possible. The determination of the exact tumor location as well as the analysis …

In this paper, measurements of the optical properties (diffuse reflectance, total and
collimated transmittance) of brain tissues in healthy rats and rats with C6-glioma were …

Fluorescence spectroscopy is an emerging tool used to differentiate normal and malignant
tissue based on the emission spectral profile from endogenous fluorophores. The goal of …