Effect of known inhibitors of ion transport on pendrin (SLC26A4) activity in a human kidney cell line
E Bernardinelli, R Costa, C Nofziger… - Cellular Physiology and …, 2016 - karger.com
Abstract Background/Aims: Pendrin is a Cl-/I-/HCO3-exchanger playing a fundamental role
in controlling blood pressure and airway function, therefore representing an attractive target …
in controlling blood pressure and airway function, therefore representing an attractive target …
Identification of allelic variants of pendrin (SLC26A4) with loss and gain of function
S Dossena, A Bizhanova, C Nofziger… - Cellular physiology and …, 2011 - karger.com
Background: Pendrin is a multifunctional anion transporter that exchanges chloride and
iodide in the thyroid, as well as chloride and bicarbonate in the inner ear, kidney and …
iodide in the thyroid, as well as chloride and bicarbonate in the inner ear, kidney and …
Pendrin: physiology, molecular biology and clinical importance
R Grimaldi, P Capuano, N Miranda… - Giornale italiano di …, 2007 - europepmc.org
Pendrin, first identified in 1997, belongs to a superfamily of anion transporters localized in
the thyroid gland, inner ear and kidney. Immunohistochemical studies have shown that …
the thyroid gland, inner ear and kidney. Immunohistochemical studies have shown that …
[HTML][HTML] Role of pendrin in acid-base balance
JH Chang, S Kim - Electrolytes & Blood Pressure: E & BP, 2009 - ncbi.nlm.nih.gov
Abstract Pendrin (SLC26A4) is a Na+-independent Cl-/HCO 3-exchanger which is
expressed in the apical membranes of type B and non-A, non-B intercalated cells within the …
expressed in the apical membranes of type B and non-A, non-B intercalated cells within the …
Pendrin: linking acid base to blood pressure
F Brazier, N Cornière, N Picard, R Chambrey… - … -European Journal of …, 2024 - Springer
Abstract Pendrin (SLC26A4) is an anion exchanger from the SLC26 transporter family which
is mutated in human patients affected by Pendred syndrome, an autosomal recessive …
is mutated in human patients affected by Pendred syndrome, an autosomal recessive …
Small-molecule inhibitors of pendrin potentiate the diuretic action of furosemide
O Cil, PM Haggie, P Phuan, JA Tan… - Journal of the American …, 2016 - journals.lww.com
Pendrin is a Cl−/HCO 3− exchanger expressed in type B and non-A, non-B intercalated cells
in the distal nephron, where it facilitates Cl− absorption and is involved in Na+ absorption …
in the distal nephron, where it facilitates Cl− absorption and is involved in Na+ absorption …
[HTML][HTML] Mechanism of anion exchange and small-molecule inhibition of pendrin
Abstract Pendrin (SLC26A4) is an anion exchanger that mediates bicarbonate (HCO3−)
exchange for chloride (Cl−) and is crucial for maintaining pH and salt homeostasis in the …
exchange for chloride (Cl−) and is crucial for maintaining pH and salt homeostasis in the …
Molecular and functional characterization of human pendrin and its allelic variants
Abstract Pendrin (SLC26A4, PDS) is an electroneutral anion exchanger transporting I-, Cl-,
HCO3-, OH-, SCN-and formate. In the thyroid, pendrin is expressed at the apical membrane …
HCO3-, OH-, SCN-and formate. In the thyroid, pendrin is expressed at the apical membrane …
Pendrin in the mouse kidney is primarily regulated by Cl− excretion but also by systemic metabolic acidosis
P Hafner, R Grimaldi, P Capuano… - … of Physiology-Cell …, 2008 - journals.physiology.org
The Cl−/anion exchanger pendrin (SLC26A4) is expressed on the apical side of renal non-
type A intercalated cells. The abundance of pendrin is reduced during metabolic acidosis …
type A intercalated cells. The abundance of pendrin is reduced during metabolic acidosis …