Background Ginseng saponin has long been used as a traditional Asian medicine and is
known to be effective in treating various kinds of pain. Ginsenoside Rf is one of the …

Ginsenosides are main pharmacoactive molecules of ginseng. The antinociceptive activity of
ginsenosides after intrathecal (it) injection was examined in formalin test. We also …

Background: Ginsenoside Rg3 is an extract of total ginseng saponins, which accounts for
4.7% of all saponins. This study aimed to identify the mechanisms of the antinociceptive …

Background: Ginseng has been used to manage various types of pain in folk medicine. This
study characterized the effect of treatment with intrathecal ginsenosides, the active …

Our recent study demonstrated that ginsenosides had antinociceptive effects by reducing
some types of pain-related behavior in mice (Yoon et al., 1998. Ginsenosides induce …

Background The aim of this study was to assess whether intraperitoneal administration of
ginseng total saponins (GTS) has antihyperalgesic effects in a rat model of incisional pain …

In this study, we investigated whether total saponin extract (TSE), ginsenoside Rb1, and Rb1
metabolite compound K, which are isolated from red ginseng, have antinociceptive effects …

Ginseng root, a traditional oriental medicine, contains more than a dozen biologically active
saponins called ginsenosides, including one present in only trace amounts called …

The aim of this study was to investigate whether ginsenoside Rf can effectively relieve pain
hypersensitivity in a neuropathic pain rat model. Neuropathic pain was induced in rats by …

Several ginsenoside (R b1, R b2, R c, R d, R e, R f, R g1 and R g3) are neuroprotective and
antinociceptive agents. In this study, we assessed the effects of these ginsenosides …