Risk assessment of endocrine disrupters: the role of toxicological studies
A Mantovani - Annals of the New York Academy of Sciences, 2006 - Wiley Online Library
Endocrine disrupters (ED) represent a good challenge for experimental toxicology. In order
to deal with several critical points relevant to risk assessment:(a) ED may induce long‐term …
to deal with several critical points relevant to risk assessment:(a) ED may induce long‐term …
Endocrine disruptors: can biological effects and environmental risks be predicted?
RJ Witorsch - Regulatory Toxicology and Pharmacology, 2002 - Elsevier
A large number of diverse nonsteroidal chemicals, referred to as xenoestrogens, bind to the
estrogen receptor (ER) and evoke biological responses. The activity of most xenoestrogens …
estrogen receptor (ER) and evoke biological responses. The activity of most xenoestrogens …
Perspective on health effects of endocrine disruptors with a focus on data gaps
RE FitzGerald - Chemical research in toxicology, 2020 - ACS Publications
Screening for endocrine disrupting properties at the molecular and cellular level is
developing rapidly, but can epidemiology bridge the gap to human health impact? Reviews …
developing rapidly, but can epidemiology bridge the gap to human health impact? Reviews …
Principles of pharmacology and toxicology also govern effects of chemicals on the endocrine system
H Autrup, FA Barile, BJ Blaauboer… - Toxicological …, 2015 - academic.oup.com
The present debate on chemicals with Hormonal activity, often termed 'endocrine disruptors',
is highly controversial and includes challenges of the present paradigms used in toxicology …
is highly controversial and includes challenges of the present paradigms used in toxicology …
An evaluation of endocrine modulators: implications for human health
DR Juberg - Ecotoxicology and Environmental Safety, 2000 - Elsevier
The potential health risk of a group of chemicals, popularly known as “endocrine disrupters,”
has generated considerable scientific debate and media attention. The endocrine disrupter …
has generated considerable scientific debate and media attention. The endocrine disrupter …
Human exposures and body burdens of endocrine-disrupting chemicals
AM Calafat, LL Needham - … -disrupting chemicals: from basic research to …, 2007 - Springer
In today's industrial societies, humans may be exposed to a wide variety of environmental
chemicals, including those with potential endocrine-disruptive properties. Although for many …
chemicals, including those with potential endocrine-disruptive properties. Although for many …
[HTML][HTML] Risk assessment of endocrine active chemicals: Identifying chemicals of regulatory concern
R Bars, I Fegert, M Gross, D Lewis, L Weltje… - Regulatory Toxicology …, 2012 - Elsevier
The European regulation on plant protection products (1107/2009)(EC, 2009a), the
revisions to the biocides Directive (COM [2009] 267)(EC, 2009b), and the regulation …
revisions to the biocides Directive (COM [2009] 267)(EC, 2009b), and the regulation …
[HTML][HTML] Endocrine disruptors: challenges and future directions in epidemiologic research
Public concern about the impact of endocrine disrupting chemicals (EDCs) on both humans
and the environment is growing steadily. Epidemiologic research provides key information …
and the environment is growing steadily. Epidemiologic research provides key information …
Uncertainties for endocrine disrupters: our view on progress
GP Daston, JC Cook, RJ Kavlock - Toxicological Sciences, 2003 - academic.oup.com
The hypothesis that hormonally active compounds in the environment—endocrine disrupters—
are having a significant impact on human and ecological health has captured the public's …
are having a significant impact on human and ecological health has captured the public's …
[HTML][HTML] Scientific principles for the identification of endocrine-disrupting chemicals: a consensus statement
R Solecki, A Kortenkamp, Å Bergman, I Chahoud… - Archives of …, 2017 - Springer
Endocrine disruption is a specific form of toxicity, where natural and/or anthropogenic
chemicals, known as “endocrine disruptors”(EDs), trigger adverse health effects by …
chemicals, known as “endocrine disruptors”(EDs), trigger adverse health effects by …