Gene amplification involves site-specific short homology-independent illegitimate recombination in Acinetobacter sp. strain ADP1

AB Reams, EL Neidle - Journal of molecular biology, 2004 - Elsevier
A system for studying gene amplification in the bacterium Acinetobacter sp. strain ADP1 was
used to isolate 105 spontaneous mutants. The method selects for the elevated expression of …

Influence of flanking homology and insert size on the transformation frequency of Acinetobacter baylyi BD413

DJ Simpson, LF Dawson, JC Fry… - Environmental …, 2007 - cambridge.org
RecA-mediated recombination requires regions of homology between donor and recipient
DNA for successful integration. This paper investigates the effect of the relationship between …

Horizontal Gene Transfer, Fitness Costs and Mobility Shape the Spread of Antibiotic Resistance Genes into Experimental Populations of Acinetobacter Baylyi

AL Sezmis, LC Woods, AY Peleg… - Molecular Biology and …, 2023 - academic.oup.com
Horizontal gene transfer (HGT) is important for microbial evolution, but how evolutionary
forces shape the frequencies of horizontally transferred genetic variants in the absence of …

Assessment of insertion sequence mobilization as an adaptive response to oxidative stress in Acinetobacter baumannii using IS-seq

MS Wright, S Mountain, K Beeri… - Journal of Bacteriology, 2017 - Am Soc Microbiol
Insertion sequence (IS) elements are found throughout bacterial genomes and contribute to
genome variation by interrupting genes or altering gene expression. Few of the more than …

Natural transformation facilitates transfer of transposons, integrons and gene cassettes between bacterial species

S Domingues, K Harms, WF Fricke, PJ Johnsen… - 2012 - journals.plos.org
We have investigated to what extent natural transformation acting on free DNA substrates
can facilitate transfer of mobile elements including transposons, integrons and/or gene …

DNA modifications impact natural transformation of Acinetobacter baumannii

N Vesel, C Iseli, N Guex, A Lemopoulos… - Nucleic Acids …, 2023 - academic.oup.com
Acinetobacter baumannii is a dangerous nosocomial pathogen, especially due to its ability
to rapidly acquire new genetic traits, including antibiotic resistance genes (ARG). In A …

Water Disinfection Byproducts Increase Natural Transformation Rates of Environmental DNA in Acinetobacter baylyi ADP1

D Mantilla-Calderon, MJ Plewa… - Environmental …, 2019 - ACS Publications
The process of natural transformation allows for the stable uptake, integration, and functional
expression of extracellular DNA. This mechanism of horizontal gene transfer has been …

Phenotypic and Physiological Changes in Acinetobacter sp. Strain DR1 with Exogenous Plasmid

J Park, W Park - Current microbiology, 2011 - Springer
The genus Acinetobacter has been recognized to take up exogenous DNA from the
environment. In this study, we conducted natural transformation with a novel diesel …

Genome plasticity in Acinetobacter: new degradative capabilities acquired by the spontaneous amplification of large chromosomal segments

AB Reams, EL Neidle - Molecular Microbiology, 2003 - Wiley Online Library
In Acinetobacter sp. ADP1, growth on benzoate requires regulation of the cat genes by two
transcriptional activators. Here, mutants were obtained from a strain lacking both activators …

Natural Transformation as a Mechanism of Horizontal Gene Transfer in Aliarcobacter butzleri

M Bonifácio, C Mateus, AR Alves, E Maldonado… - Pathogens, 2021 - mdpi.com
Aliarcobacter butzleri is an emergent enteropathogen, showing high genetic diversity, which
likely contributes to its adaptive capacity to different environments. Whether natural …