[HTML][HTML] Notch1 pathway-mediated microRNA-151-5p promotes gastric cancer progression

KW Hsu, WL Fang, KH Huang, TT Huang, HC Lee… - Oncotarget, 2016 - ncbi.nlm.nih.gov
Gastric carcinoma is the third leading cause of lethal cancer worldwide. Previous studies
showed that Notch1 receptor intracellular domain (N1IC), the activated form of Notch1 …

[HTML][HTML] The reciprocal regulation loop of Notch2 pathway and miR-23b in controlling gastric carcinogenesis

TT Huang, YH Ping, AM Wang, CC Ke, WL Fang… - Oncotarget, 2015 - ncbi.nlm.nih.gov
Gastric carcinoma is one of the most common malignancies and the third highest cause of
global cancer-related death. Notch2 receptor intracellular domain (N2IC), the activated form …

[HTML][HTML] Tumor-Suppressive MicroRNA-708 Targets Notch1 to Suppress Cell Proliferation and Invasion in Gastric Cancer

X Li, X Zhong, X Pan, Y Ji - Oncology research, 2018 - ncbi.nlm.nih.gov
Growing evidence has demonstrated that numerous microRNAs (miRNAs) may participate
in the regulation of gastric carcinogenesis and progression. This phenomenon suggests that …

[HTML][HTML] NOTCH3, a crucial target of miR-491-5p/miR-875-5p, promotes gastric carcinogenesis by upregulating PHLDB2 expression and activating Akt pathway

W Kang, J Zhang, T Huang, Y Zhou, CC Wong… - Oncogene, 2021 - nature.com
Aberrant Notch activation has been implicated in multiple malignancies and the
identification of NOTCH receptors and related pathways is critical for targeted therapy. In this …

miR‐124 interacts with the Notch1 signalling pathway and has therapeutic potential against gastric cancer

L Jiang, T Lin, C Xu, S Hu, Y Pan… - Journal of cellular and …, 2016 - Wiley Online Library
Aberrant Notch signalling plays an important role in cancer progression. However, little is
known about the interaction between mi RNA and the Notch signalling pathway and its role …

MicroRNA-140-5p inhibits cell proliferation, migration and promotes cell apoptosis in gastric cancer through the negative regulation of THY1-mediated Notch signaling

K Wu, J Zou, C Lin, ZG Jie - Bioscience reports, 2019 - portlandpress.com
Studies have highlighted the importance of microRNAs (miRs) in the development of various
cancers, including gastric cancer (GC), a commonly occurring malignancy, accompanied by …

[HTML][HTML] microRNA-139-5p exerts tumor suppressor function by targeting NOTCH1 in colorectal cancer

L Zhang, Y Dong, N Zhu, H Tsoi, Z Zhao, CW Wu… - Molecular cancer, 2014 - Springer
Abstract Background miR-139-5p was identified to be significantly down-regulated in colon
tumor tissues by miRNA array. We aimed to clarify its biological function, molecular …

miR-93-5p/IFNAR1 axis promotes gastric cancer metastasis through activating the STAT3 signaling pathway

DH Ma, BS Li, JJ Liu, YF Xiao, X Yong, SM Wang… - Cancer letters, 2017 - Elsevier
Aberrant expression of microRNAs (miRNAs) plays an important role in gastric cancer (GC)
development. miR-93-5p has shown opposing functions in different types of cancers, but the …

[HTML][HTML] MicroRNA-93-5p promotes epithelial-mesenchymal transition in gastric cancer by repressing tumor suppressor AHNAK expression

E Shen, X Wang, X Liu, M Lv, L Zhang, G Zhu… - Cancer cell …, 2020 - Springer
Background Gastric cancer (GC) is a common cause of cancer-related mortality worldwide,
and microRNAs (miRNAs) have been shown to play an important role in GC development …

miR-935 suppresses gastric signet ring cell carcinoma tumorigenesis by targeting Notch1 expression

C Yan, J Yu, W Kang, Y Liu, Z Ma, L Zhou - Biochemical and biophysical …, 2016 - Elsevier
Gastric signet ring cell carcinoma (GSRCC) is a unique pathological type of gastric
carcinoma that is extremely invasive and has a poor prognosis. Expression of microRNAs …