Real-world vinflunine outcomes in bladder cancer in a single-institution study: moving beyond clinical trials

G Moriceau, A Vallard, R Rivoirard, B Méry… - Clinical genitourinary …, 2015 - Elsevier
Purpose Intravenous vinflunine 320 mg/m 2 every 3 weeks plus best supportive care
resulted in better overall survival in comparison with best supportive care alone for eligible …

From clinical trials to the front line: Vinflunine for treatment of urothelial cell carcinoma at the National Cancer Institute of Naples

G Facchini, C Della Pepa, C Cavaliere… - Frontiers in …, 2016 - frontiersin.org
Background: The efficacy of Vinflunine, after failure of platinum-based chemotherapy in
patients with metastatic or recurrent Transitional Cell Cancer of the Urothelial Tract, TCCU …

Vinflunine in the treatment of advanced bladder cancer

R Mamtani, DJ Vaughn - Expert review of anticancer therapy, 2011 - Taylor & Francis
Accounting for 14,000 deaths in the USA last year, research informs us that advanced
bladder cancer is a lethal disease with a median survival that has remained a little over 1 …

Treatment of relapsed urothelial bladder cancer with vinflunine: real-world evidence by the Hellenic Genitourinary Cancer Group

N Pistamaltzian, K Tzannis, V Pissanidou… - Anti-Cancer …, 2016 - journals.lww.com
Relapsed urothelial cancer represents an unmet medical need. Vinflunine is a third-
generation antimicrotubuline inhibitor and is currently the only approved drug for second …

Vinflunine in routine clinical practice for the treatment of advanced or metastatic urothelial cell carcinoma-data from a prospective, multicenter experience

M Retz, P De Geeter, PJ Goebell, U Matz, W De Schultz… - BMC cancer, 2015 - Springer
Background Vinflunine is recommended in the European guideline for the treatment of
advanced or metastatic urothelial cell carcinoma (UCC) after failure of platinum-based …

Efficacy and safety of Vinflunine for advanced or metastatic urothelial carcinoma in routine practice based on the French multi-centre CURVE study

J Médioni, M Di Palma, A Guillot, D Spaeth… - BMC cancer, 2016 - Springer
Background To retrospectively assess the efficacy and safety of Vinflunine (VFL) under
routine conditions and identify overall survival (OS) prognostic factors. Methods Twenty …

Safety and effectiveness of vinflunine in patients with metastatic transitional cell carcinoma of the urothelial tract after failure of one platinum-based systemic therapy in …

D Castellano, J Puente, G De Velasco, I Chirivella… - BMC cancer, 2014 - Springer
Background Patients with transitional cell carcinoma of the urothelial tract (TCCU) who fail
initial platinum-based chemotherapy for advanced disease represent a challenge in daily …

Phase III trial of vinflunine plus best supportive care compared with best supportive care alone after a platinum-containing regimen in patients with advanced …

J Bellmunt, C Théodore, T Demkov… - Journal of Clinical …, 2009 - ascopubs.org
Purpose Vinflunine (VFL) is a new microtubule inhibitor that has activity against transitional
cell carcinoma of urothelial tract (TCCU). We conducted a randomized phase III study of VFL …

Vinflunine for the treatment of advanced or metastatic transitional cell carcinoma of the urothelial tract: an evidence-based review of safety, efficacy, and place in …

SC Brousell, JJ Fantony, MG Van Noord… - Core …, 2018 - Taylor & Francis
Background: A systematic review and meta-analysis of the use of systemic vinflunine (VIN)
in the treatment of urothelial carcinoma (UC) was performed to evaluate its efficacy based on …

[HTML][HTML] VICTOR: Vinflunine in advanced metastatic transitional cell carcinoma of the urothelium: A retrospective analysis of the use of vinflunine in multi-centre real …

SA Hussain, J Ansari, R Huddart… - International …, 2017 - spandidos-publications.com
There is no standard of care in the UK or Ireland for second-line chemotherapy for patients
with advanced transitional cell carcinoma (TCCU). Vinflunine is approved for TCCU patients …