Long noncoding RNA: an emerging paradigm of cancer research

MT Qiu, JW Hu, R Yin, L Xu - Tumor Biology, 2013 - Springer
Recent studies have demonstrated the importance of non-protein coding part of human
genome in carcinogenesis and metastasis. Among numerous kinds of non-protein coding …

Roles of long noncoding RNAs in gastric cancer and their clinical applications

W Sun, Y Yang, C Xu, Y Xie, J Guo - Journal of cancer research and …, 2016 - Springer
Purpose Gastric cancer ranks as the most common cancer in the world. However, the
progresses of its diagnosis and treatment are still not satisfactory. The purpose of this study …

[HTML][HTML] Long non-coding RNA in cancer

N Hauptman, D Glavač - International journal of molecular sciences, 2013 - mdpi.com
Long non-coding RNAs (lncRNAs) are pervasively transcribed in the genome and are
emerging as new players in tumorigenesis due to their various functions in transcriptional …

Long non-coding RNAs in cancer: implications for diagnosis, prognosis, and therapy

Y Qian, L Shi, Z Luo - Frontiers in medicine, 2020 - frontiersin.org
Long non-coding RNAs (lncRNAs) are major components of cellular transcripts that are
arising as important players in various biological pathways. They have received extensive …

Long noncoding RNAs as new architects in cancer epigenetics, prognostic biomarkers, and potential therapeutic targets

D Meseure, K Drak Alsibai, A Nicolas… - BioMed research …, 2015 - Wiley Online Library
Recent advances in genome‐wide analysis have revealed that 66% of the genome is
actively transcribed into noncoding RNAs (ncRNAs) while less than 2% of the sequences …

Long non-coding RNA LINC02446 suppresses the proliferation and metastasis of bladder cancer cells by binding with EIF3G and regulating the mTOR signalling …

X Zhang, J Zhang, W Zhao, X Dong, P Xin, X Liu… - Cancer Gene …, 2021 - nature.com
Accumulating evidence has been obtained to understand the mechanisms of long non-
coding RNAs (lncRNAs) in bladder cancer (BC). However, due to the recurrence and …

[HTML][HTML] Identification and validation of a prognostic immune-related lncRNA signature in bladder cancer

K Zhao, Q Zhang, T Zeng, J Zhang… - Translational …, 2021 - ncbi.nlm.nih.gov
Background Recently, researches have implied that immune-related lncRNAs (IR-lncRNAs)
have a vital role in tumor occurrence and development. However, the study in bladder …

Current insights into long non-coding RNAs in renal cell carcinoma

M Seles, GC Hutterer, T Kiesslich, K Pummer… - International journal of …, 2016 - mdpi.com
Renal cell carcinoma (RCC) represents a deadly disease with rising mortality despite
intensive therapeutic efforts. It comprises several subtypes in terms of distinct …

Pathological bases and clinical impact of long noncoding RNAs in prostate cancer: a new budding star

T Xu, C Lin, S Cheng, J Min, L Li, X Meng, C Huang… - Molecular cancer, 2018 - Springer
Long non-coding RNAs (lncRNAs) are functional RNAs longer than 200 nucleotides. Recent
advances in the non-protein coding part of human genome analysis have discovered …

[HTML][HTML] Long non-coding RNAs in colorectal cancer

X Xie, B Tang, YF Xiao, R Xie, BS Li, H Dong, JY Zhou… - Oncotarget, 2016 - ncbi.nlm.nih.gov
Colorectal cancer (CRC) is one of the leading causes of cancer-related death worldwide.
Despite substantial progress in understanding the molecular mechanisms and treatment of …