Secondary brain injury after aneurysmal subarachnoid hemorrhage (SAH-SBI) contributes to
poor outcomes in patients after rupture of an intracranial aneurysm. The lack of diagnostic …

Background Aneurysmal subarachnoid hemorrhage (aSAH) is often complicated by the
occurrence of delayed ischemic neurologic deficits (DIND), which impairs the clinical …

Objectives Cerebrospinal fluid hemoglobin has been positioned as a potential biomarker
and drug target for aneurysmal subarachnoid hemorrhage-related secondary brain injury …

Objective Anemia predicts poor outcome following aneurysmal subarachnoid hemorrhage
(SAH). We hypothesized that this association would be stronger among patients with more …

Delayed ischemic neurological deficit (DIND) is a major driver of adverse outcomes in
patients with aneurysmal subarachnoid hemorrhage (aSAH), defining an unmet need for …

Background and Purpose—The optimal hemoglobin (Hgb) target after aneurysmal
subarachnoid hemorrhage is not precisely known. We sought to examine the threshold of …

After intracerebral hemorrhage (ICH), the brain parenchyma is exposed to blood containing
red blood cells (RBCs) and consequently to its lysis products. Iron-rich hemoglobin (Hb) is …

Aneurysmal subarachnoid hemorrhage (aSAH) is a devastating form of stroke frequently
affecting young to middle-aged adults, with an unmet need to improve outcome. This special …

Object Experimental studies have demonstrated the crucial role of posthemorrhagic
erythrocyte catabolism in the pathogenesis of subarachnoid hemorrhage (SAH). The authors …

Survivors of cerebral aneurysm rupture are at risk for significant morbidity and neurological
deficits. Much of this is related to the effects of blood in the subarachnoid space which …