Common susceptibility loci for male breast cancer

S Maguire, E Perraki, K Tomczyk… - JNCI: Journal of the …, 2021 - academic.oup.com
Background The etiology of male breast cancer (MBC) is poorly understood. In particular,
the extent to which the genetic basis of MBC differs from female breast cancer (FBC) is …

Male breast cancer: from molecular genetics to clinical management

M Pensabene, C Von Arx, M De Laurentiis - Cancers, 2022 - mdpi.com
Simple Summary Male breast cancer (MBC) is a rare disease. Genetic factors predispose to
male breast cancer. Germline and/or genetic and/or epigenetic alterations at the somatic …

Family history of breast cancer in men with non-BRCA male breast cancer: implications for cancer risk counseling

GS Calip, J Kidd, R Bernhisel, HC Cox, J Saam… - Breast cancer research …, 2021 - Springer
Purpose The role of genetic predisposition in male breast cancer (MBC) patients who test
negative for a BRCA mutation is unclear. The aim of this study is to define the association …

Male breast cancer in a multi-gene panel testing cohort: insights and unexpected results

M Pritzlaff, P Summerour, R McFarland, S Li… - Breast cancer research …, 2017 - Springer
Purpose Genetic predisposition to male breast cancer (MBC) is not well understood. The
aim of this study was to better define the predisposition genes contributing to MBC and the …

Insight into genetic susceptibility to male breast cancer by multigene panel testing: Results from a multicenter study in Italy

P Rizzolo, V Zelli, V Silvestri, V Valentini… - … Journal of Cancer, 2019 - Wiley Online Library
Breast cancer (BC) in men is rare and genetic predisposition is likely to play a relevant role
in its etiology. Inherited mutations in BRCA1/2 account for about 13% of all cases and …

Genetic landscape of male breast cancer

FAB Campos, E Rouleau, GT Torrezan, DM Carraro… - Cancers, 2021 - mdpi.com
Simple Summary Male breast cancer is a rare disease, representing around 0.5% of the
malignances in men. Although they receive the same treatment as women with breast …

Male breast cancer is not congruent with the female disease

IS Fentiman - Critical reviews in oncology/hematology, 2016 - Elsevier
It has become customary to extrapolate from the results of treatment trials for female
breastcancer and apply them to males with the disease. In the absence of results from …

Association of low-penetrance alleles with male breast cancer risk and clinicopathological characteristics: results from a multicenter study in Italy

L Ottini, V Silvestri, C Saieva, P Rizzolo, I Zanna… - Breast cancer research …, 2013 - Springer
It is well-known that male breast cancer (MBC) susceptibility is mainly due to high-
penetrance BRCA1/2 mutations. Here, we investigated whether common low-penetrance …

Male breast cancer: results of the application of multigene panel testing to an Italian cohort of patients

G Tedaldi, M Tebaldi, V Zampiga, I Cangini, F Pirini… - Diagnostics, 2020 - mdpi.com
Male breast cancer (MBC) is a rare tumor, accounting for less than 1% of all breast cancers.
In MBC, genetic predisposition plays an important role; however, only a few studies have …

Familial associations of male breast cancer with other cancers

G Zheng, H Yu, A Hemminki, A Försti… - Breast Cancer Research …, 2017 - Springer
Purpose Male breast cancer is associated with female breast cancer in families but whether
male breast cancer clusters with other discordant cancers has not been studied. As …