Dietary DHA supplementation in an APP/PS1 transgenic rat model of AD reduces behavioral and Aβ pathology and modulates Aβ oligomerization
E Teng, K Taylor, T Bilousova, D Weiland, T Pham… - Neurobiology of …, 2015 - Elsevier
Increased dietary consumption of docosahexaenoic acid (DHA) is associated with
decreased risk for Alzheimer's disease (AD). These effects have been postulated to arise …
decreased risk for Alzheimer's disease (AD). These effects have been postulated to arise …
Docosahexaenoic acid stimulates non‐amyloidogenic APP processing resulting in reduced Aβ levels in cellular models of Alzheimer's disease
C Sahlin, FE Pettersson, LNG Nilsson… - European Journal of …, 2007 - Wiley Online Library
Epidemiological studies suggest that a high intake of polyunsaturated fatty acids, such as
docosahexaenoic acid (DHA), is associated with a reduced risk of Alzheimer's disease …
docosahexaenoic acid (DHA), is associated with a reduced risk of Alzheimer's disease …
A diet enriched with the omega-3 fatty acid docosahexaenoic acid reduces amyloid burden in an aged Alzheimer mouse model
Epidemiological studies suggest that increased intake of the omega-3 (n-3) polyunsaturated
fatty acid (PUFA) docosahexaenoic acid (DHA) is associated with reduced risk of …
fatty acid (PUFA) docosahexaenoic acid (DHA) is associated with reduced risk of …
Docosahexaenoic acid protects from amyloid and dendritic pathology in an Alzheimer's disease mouse model
GM Cole, SA Frautschy - Nutrition and health, 2006 - journals.sagepub.com
Genetic data argues that Alzheimer's disease (AD) can be initiated by aggregates of a 42
amino acid beta amyloid peptide (Aβ42). The Aβ aggregates, notably small oligomer …
amino acid beta amyloid peptide (Aβ42). The Aβ aggregates, notably small oligomer …
Endogenous docosahexaenoic acid (dha) prevents aβ1–42 oligomer-induced neuronal injury
The intake of the polyunsaturated fatty acid docosahexaenoic acid (DHA) or n-3 fatty acid
has been associated with reduced risk of Alzheimer's disease (AD) in epidemiological …
has been associated with reduced risk of Alzheimer's disease (AD) in epidemiological …
Dietary docosahexaenoic acid and docosapentaenoic acid ameliorate amyloid-β and tau pathology via a mechanism involving presenilin 1 levels
KN Green, H Martinez-Coria, H Khashwji… - Journal of …, 2007 - Soc Neuroscience
The underlying cause of sporadic Alzheimer disease (AD) is unknown, but a number of
environmental and genetic factors are likely to be involved. One environmental factor that is …
environmental and genetic factors are likely to be involved. One environmental factor that is …
[HTML][HTML] DHA supplemented in peptamen diet offers no advantage in pathways to amyloidosis: is it time to evaluate composite lipid diet?
Z Amtul, M Keet, L Wang, P Merrifield, D Westaway… - PLoS …, 2011 - journals.plos.org
Numerous reports have documented the beneficial effects of dietary docosahexaenoic acid
(DHA) on beta-amyloid production and Alzheimer's disease (AD). However, none of these …
(DHA) on beta-amyloid production and Alzheimer's disease (AD). However, none of these …
Docosahexaenoic acid prevents neuronal apoptosis induced by soluble amyloid‐β oligomers
S Florent, C Malaplate‐Armand… - Journal of …, 2006 - Wiley Online Library
A growing body of evidence supports the notion that soluble oligomers of amyloid‐β (Aβ)
peptide interact with the neuronal plasma membrane, leading to cell injury and inducing …
peptide interact with the neuronal plasma membrane, leading to cell injury and inducing …
Docosahexaenoic acid supplementation and cognitive decline in Alzheimer disease: a randomized trial
Context Docosahexaenoic acid (DHA) is the most abundant long-chain polyunsaturated fatty
acid in the brain. Epidemiological studies suggest that consumption of DHA is associated …
acid in the brain. Epidemiological studies suggest that consumption of DHA is associated …
Neuroprotective action of omega-3 polyunsaturated fatty acids against neurodegenerative diseases: evidence from animal studies
Studies in animals clearly show that oral intake of docosahexaenoic acid (DHA) can alter
brain DHA concentrations and thereby modify brain functions. This provides us with an …
brain DHA concentrations and thereby modify brain functions. This provides us with an …