Protective effect and mechanism of docosahexaenoic acid on the cognitive function in female APP/PS1 mice
N Bie, J Li, C Li, R Lian, L Qin, C Wang - Food & Function, 2021 - pubs.rsc.org
Docosahexaenoic acid (DHA) has been studied for many years owing to its protective effect
on the decline in brain function. DHA intake reduces the risk of Alzheimer's disease (AD) …
on the decline in brain function. DHA intake reduces the risk of Alzheimer's disease (AD) …
[HTML][HTML] Dietary DHA supplementation causes selective changes in phospholipids from different brain regions in both wild type mice and the Tg2576 mouse model of …
C Bascoul-Colombo, IA Guschina, BH Maskrey… - … et Biophysica Acta (BBA …, 2016 - Elsevier
Alzheimer's disease (AD) is of major concern in ageing populations and we have used the
Tg2576 mouse model to understand connections between brain lipids and amyloid …
Tg2576 mouse model to understand connections between brain lipids and amyloid …
Towards a nutritional approach for prevention of Alzheimer's disease: biochemical and cellular aspects
S Florent-Béchard, C Malaplate-Armand… - Journal of the …, 2007 - Elsevier
Alzheimer's disease (AD) is a major public health concern in all countries. Although the
precise cause of AD is still unknown, a growing body of evidence supports the notion that …
precise cause of AD is still unknown, a growing body of evidence supports the notion that …
[引用][C] O1‐04‐01: Results of the MIDAS trial: Effects of docosahexaenoic acid on physiological and safety parameters in age‐related cognitive decline
K Yurko‐Mauro, D McCarthy… - Alzheimer's & …, 2009 - Wiley Online Library
Background Docosahexaenoic acid,(DHA), the principle omega-3 fatty acid in brain, plays
an important role in neural function. Decreases in plasma DHA are associated with cognitive …
an important role in neural function. Decreases in plasma DHA are associated with cognitive …
Arachidonic or docosahexaenoic acid diet prevents memory impairment in Tg2576 mice
T Hosono, A Mouri, K Nishitsuji… - Journal of …, 2015 - content.iospress.com
It is believed that the amyloid β-protein (Aβ) plays a causative role in the development of
Alzheimer's disease (AD). The amyloid-β protein precursor (AβPP), a substrate of Aβ, and β …
Alzheimer's disease (AD). The amyloid-β protein precursor (AβPP), a substrate of Aβ, and β …
Fatty acid facts, Part IV: docosahexaenoic acid and Alzheimer's disease. A story of mice, men and fish.
EK Pauwels, D Volterrani, G Mariani… - Drug news & …, 2009 - europepmc.org
The primary pathological hallmark of Alzheimer's disease (AD) is neurodegeneration by
neuronal cell death caused by the development of aggregates of beta-amyloid peptide …
neuronal cell death caused by the development of aggregates of beta-amyloid peptide …
DHA and cholesterol containing diets influence Alzheimer-like pathology, cognition and cerebral vasculature in APPswe/PS1dE9 mice
CR Hooijmans, C Van der Zee, PJ Dederen… - Neurobiology of …, 2009 - Elsevier
Cholesterol and docosahexenoic acid (DHA) may affect degenerative processes in
Alzheimer's Disease (AD) by influencing Aβ metabolism indirectly via the vasculature. We …
Alzheimer's Disease (AD) by influencing Aβ metabolism indirectly via the vasculature. We …
Deuterated polyunsaturated fatty acids reduce brain lipid peroxidation and hippocampal amyloid β-peptide levels, without discernable behavioral effects in an APP …
Alzheimer's disease (AD) involves progressive deposition of amyloid β-peptide (Aβ),
synapse loss, and neuronal death, which occur in brain regions critical for learning and …
synapse loss, and neuronal death, which occur in brain regions critical for learning and …
Endogenous conversion of omega-6 into omega-3 fatty acids improves neuropathology in an animal model of Alzheimer's disease
M Lebbadi, C Julien, A Phivilay… - Journal of …, 2011 - content.iospress.com
Dietary supplementation with n-3 polyunsaturated fatty acids (n-3 PUFA) reduces amyloid-β
(Aβ) and tau pathology and improves cognitive performance in animal models of Alzheimer's …
(Aβ) and tau pathology and improves cognitive performance in animal models of Alzheimer's …
Is Alzheimer's disease a synaptic disorder?
M Pomponi, P Bria, M Pomponi - Journal of Alzheimer's …, 2008 - content.iospress.com
Background:: In Alzheimer's disease (AD), the common symptom is loss of memory.
Learning and memory are associated with amoeboid movements of synaptic endings …
Learning and memory are associated with amoeboid movements of synaptic endings …