Determination of carcinogenic tobacco-specific nitrosamines in mainstream smoke from US-brand and non-US-brand cigarettes from 14 countries

W Wu, L Zhang, RB Jain, DL Ashley… - Nicotine & tobacco …, 2005 - academic.oup.com
Tobacco-specific nitrosamines (TSNAs) comprise one of the major classes of carcinogenic
compounds in mainstream cigarette smoke. As part of collaborative efforts between the …

Tobacco-specific nitrosamines in tobacco from US brand and non-US brand cigarettes

DL Ashley, MD Beeson, DR Johnson… - Nicotine & tobacco …, 2003 - academic.oup.com
Tobacco-specific nitrosamines (TSNAs) are one of the major classes of carcinogens found in
tobacco products. As part of collaborative efforts to reduce tobacco use and resulting …

Simultaneous determination of five tobacco-specific nitrosamines in mainstream cigarette smoke by isotope dilution liquid chromatography/electrospray ionization …

W Wu, DL Ashley, CH Watson - Analytical Chemistry, 2003 - ACS Publications
Tobacco-specific nitrosamines (TSNAs) have been previously implicated as a source of
carcinogenicity in tobacco and cigarette smoke. Accurate quantification of these chemicals is …

Carcinogenic tobacco-specific N-nitrosamines in US cigarettes: three decades of remarkable neglect by the tobacco industry

I Stepanov, A Knezevich, L Zhang… - Tobacco …, 2012 - tobaccocontrol.bmj.com
Background Modification of tobacco curing methods and other changes in cigarette
manufacturing techniques could substantially reduce the levels of tobacco-specific …

Simultaneous determination of four tobacco-specific N-nitrosamines in mainstream smoke for Chinese Virginia cigarettes by liquid chromatography–tandem mass …

W Xiong, H Hou, X Jiang, G Tang, Q Hu - Analytica chimica acta, 2010 - Elsevier
A liquid chromatography–tandem mass spectrometry (LC–MS/MS) method for determining
four tobacco-specific N-nitrosamines (TSNAs) in mainstream smoke from Chinese Virginia …

Tobacco-specific nitrosamines in mainstream smoke of West Gennan cigarettes-tar alone is not a sufficient index for the carcinogenic potential of cigarette smoke

S Fischer, B Spiegelhalder, R Preussmann - Carcinogenesis, 1989 - academic.oup.com
Fifty-five types of commercial cigarettes on the West German market were analyzed for
tobacco-specific nitrosamines (TSNA) in mainstream smoke. The cigarettes included filter …

Development of a quantitative method for the analysis of tobacco-specific nitrosamines in mainstream cigarette smoke using isotope dilution liquid chromatography …

KA Wagner, NH Finkel, JE Fossett… - Analytical …, 2005 - ACS Publications
An improved method has been developed for the determination of the four major tobacco-
specific nitrosamines (TSNA) in mainstream cigarette smoke. The new method offers …

[HTML][HTML] TSNA levels in machine-generated mainstream cigarette smoke: 35 years of data

S Appleton, RM Olegario, PJ Lipowicz - Regulatory Toxicology and …, 2013 - Elsevier
This paper characterizes historical and current tobacco specific nitrosamine (TSNA) levels in
mainstream (MS) cigarette smoke of US commercial cigarettes. To conduct this analysis, we …

Tobacco-specific nitrosamines in the tobacco and mainstream smoke of US commercial cigarettes

SH Edwards, LM Rossiter, KM Taylor… - Chemical research in …, 2017 - ACS Publications
Tobacco-specific nitrosamines (TSNAs) are N-nitroso-derivatives of pyridine-alkaloids (eg,
nicotine) present in tobacco and cigarette smoke. Two TSNAs, N′-nitrosonornicotine (NNN) …

Effect of differing levels of tobacco-specific nitrosamines in cigarette smoke on the levels of biomarkers in smokers

DL Ashley, RJ O'Connor, JT Bernert, CH Watson… - … , biomarkers & prevention, 2010 - AACR
Background: Smokers are exposed to significant doses of carcinogens, including tobacco-
specific nitrosamines (TSNA). Previous studies have shown significant global differences in …