Is There an Obesity Paradox for Outcomes in Atrial Fibrillation? A Systematic Review and Meta-Analysis of Non–Vitamin K Antagonist Oral Anticoagulant Trials

M Proietti, E Guiducci, P Cheli, GYH Lip - Stroke, 2017 - Am Heart Assoc
Background and Purpose—Obesity is a risk factor for all-cause and cardiovascular death
but, despite this, an inverse relationship between overweight or obesity and a better …

Non-vitamin K antagonist oral anticoagulant for atrial fibrillation in obese patients

SY Wang, RP Giugliano - The American Journal of Cardiology, 2020 - Elsevier
Highlights•Obesity is an important risk factor for atrial fibrillation.•Despite “obesity paradox”
in atrial fibrillation, patient weight loss preferred.•Oral anticoagulants may be more …

Association of body mass index with clinical outcomes in patients with atrial fibrillation: a report from the FANTASIIA registry

V Bertomeu‐Gonzalez, J Moreno‐Arribas… - Journal of the …, 2020 - Am Heart Assoc
Background Obesity and atrial fibrillation (AF) frequently coexist and independently increase
mortality. We sought to assess the association between obesity and adverse events in …

Body mass index and adverse outcomes in elderly patients with atrial fibrillation: the AMADEUS trial

K Senoo, GYH Lip - Stroke, 2016 - Am Heart Assoc
Background and Purpose—Obesity has been associated with increased cardiovascular risk
in atrial fibrillation, but little is known in elderly patients with atrial fibrillation. Methods—Post …

The obesity paradox for outcomes in atrial fibrillation: Evidence from an exposure‐effect analysis of prospective studies

X Liu, L Guo, K Xiao, W Zhu, M Liu, R Wan… - Obesity …, 2020 - Wiley Online Library
The impact of obesity on the prognosis of atrial fibrillation (AF) remains controversial. We
conducted an exposure‐effect meta‐analysis of prospective studies to clarify the relationship …

The 'obesity paradox'in atrial fibrillation: observations from the ARISTOTLE (Apixaban for Reduction in Stroke and Other Thromboembolic Events in Atrial Fibrillation) …

RK Sandhu, J Ezekowitz, U Andersson… - European Heart …, 2016 - academic.oup.com
Aims The prognostic implication of adiposity on clinical outcomes in atrial fibrillation (AF)
patients treated with oral anticoagulation is unclear. Methods and results A total of 17 913 …

Increased risk of major bleeding in underweight patients with atrial fibrillation who were prescribed non-vitamin K antagonist oral anticoagulants

CS Park, EK Choi, HM Kim, SR Lee, MJ Cha, S Oh - Heart Rhythm, 2017 - Elsevier
Background There is a paucity of evidence regarding the effects of non-vitamin K antagonist
oral anticoagulants (NOACs) in underweight patients with atrial fibrillation (AF). Objective …

Meta-analysis comparing direct oral anticoagulants versus warfarin in morbidly obese patients with atrial fibrillation

K Kido, M Shimizu, T Shiga, M Hashiguchi - The American journal of …, 2020 - Elsevier
Highlights•Direct oral anticoagulants did not increase stroke or systemic embolism event
rate.•Direct oral anticoagulants had lower major bleeding rate than warfarin.•Direct oral …

Efficacy and Safety of Non–Vitamin-K Antagonist Oral Anticoagulants Versus Warfarin Across the Spectrum of Body Mass Index and Body Weight: An Individual …

SM Patel, E Braunwald, J Steffel, G Boriani… - Circulation, 2024 - Am Heart Assoc
BACKGROUND: The efficacy and safety of non–vitamin-K antagonist oral anticoagulants
(NOACs) across the spectrum of body mass index (BMI) and body weight (BW) remain …

[HTML][HTML] Effects of body mass index on risks for ischemic stroke, thromboembolism, and mortality in Chinese atrial fibrillation patients: a single-center experience

HJ Wang, QJ Si, ZL Shan, YT Guo, K Lin, XN Zhao… - PLoS …, 2015 - journals.plos.org
Background Obesity is considered to be related to recurrence of atrial fibrillation (AF), left
atrial thrombus formation, and atrial remodeling. However, whether obesity is an …