Recently, much attention has been paid to chronic neuro-inflammatory condition underlying
neuropathic pain. It is generally linked with thermal hyperalgesia and tactile allodynia. It …

Chronic neuroinflammation may be a critical component of intractable inflammatory
diseases, including neuropathic pain. Because angiogenesis as a result of vascular …

Our nervous system is capable of detecting a wide range of stimuli which can evoke pain.
These can generate a short-term sensations (acute pain) which usually resolves. However …

Chronic neuropathic pain (CNP) refers to pain that lasts for more than three months due to a
disease or an injury to the somatosensory nervous system. The incidence of CNP has been …

Pain can be induced by tissue injuries, diseases and infections. The interactions between
the peripheral nervous system (PNS) and immune system are primary actions in pain …

Among different forms of persistent pain, neuropathic pain presents as a most difficult task
for basic researchers and clinicians. Despite recent rapid development of neuroscience and …

Neuropathic pain is caused by functional abnormalities of structural lesions in the peripheral
or central nervous system, and occurs without peripheral nociceptor stimulation. Many …

Chronic pain syndrome is a heterogeneous group of diseases characterized by several
pathological mechanisms. One in five adults in Europe may experience chronic pain. In …

Background Understanding the underlying mechanisms of neuropathic pain caused by
damage to the peripheral nervous system remains challenging and could lead to …

There has been recent evidence showing the correlation between neuroinflammation owing
to the chemokine–cytokine network and neuropathic pain. Chemokines and cytokines are …