Schwann cells are components of the peripheral nerve myelin sheath, which supports and
nourishes axons. Upon injury of the trigeminal nerve, Schwann cells are activated and …

Synovial fibrosis is one of the most dominant histopathological changes in osteoarthritis of
the knee (KOA), and activation of vascular endothelial cells in synovial fibrosis is both an …

Neuropathic pain is caused by structural lesion leading to functional abnormalities in central
and peripheral nervous system. Neuropathic pain in itself is not always a disease, as it …

Neuropathic pain refers to pain that originates from pathology of the nervous system.
Diabetes, infection (herpes zoster), nerve compression, nerve trauma," channelopathies," …

Chronic pain such as neuropathic pain, osteoarthritic pain, or abnormal pain associated with
neurological diseases represents a debilitating condition which strongly affects the quality of …

Despite tremendous research effort in the field, our current understanding of the molecular
mechanisms underlying neuropathic pain is still incomplete. In the present study, our …

Chronic pain is a debilitating condition that influences the social, economic, and
psychological aspects of patients' lives. Hence, the need for better treatment is drawing …

Background: Neuropathic pain (NP) is an incurable disease caused by a primary lesion in
the nervous system. NP is a progressive nervous system disease that results from poorly …

Neuropathic pain is a pathological symptom experienced worldwide by patients suffering
with nervous system dysfunction caused by various diseases. Treatment of neuropathic pain …

Pain has been considered as a concept of sensation that we feel as a reaction to the
stimulus of our surrounding, putting us in harm's way and acting as a form of defense …