The neuropathic pain: An overview of the current treatment and future therapeutic approaches
E Cavalli, S Mammana, F Nicoletti… - International journal …, 2019 - journals.sagepub.com
Neuropathic pain is characterized by abnormal hypersensitivity to stimuli (hyperalgesia) and
nociceptive responses to non-noxious stimuli (allodynia). The conditions and the …
nociceptive responses to non-noxious stimuli (allodynia). The conditions and the …
[HTML][HTML] On the therapeutic targets and pharmacological treatments for pain relief following spinal cord injury: A mechanistic review
Spinal cord injury (SCI) is globally considered as one of the most debilitating disorders,
which interferes with daily activities and life of the affected patients. Despite many …
which interferes with daily activities and life of the affected patients. Despite many …
[HTML][HTML] Bioinformatics analysis identifies p53 as a candidate prognostic biomarker for neuropathic pain
Y Gao, N Sun, L Wang, Y Wu, L Ma, J Hong… - Frontiers in …, 2018 - frontiersin.org
Neuropathic pain (NP) is a type of chronic pain that is different from the common type of
pain. The mechanisms of NP are still poorly understood. Exploring the key genes and …
pain. The mechanisms of NP are still poorly understood. Exploring the key genes and …
Systematic analysis of critical genes and pathways identified a signature of neuropathic pain after spinal cord injury
Z Li, H Bai, R Zhang, B Chen, J Wang… - European Journal of …, 2022 - Wiley Online Library
Spinal cord injury (SCI) damages sensory systems, producing chronic neuropathic pain that
is resistant to medical treatment. The specific mechanisms underlying SCI‐induced …
is resistant to medical treatment. The specific mechanisms underlying SCI‐induced …
Chemokines in neuron–glial cell interaction and pathogenesis of neuropathic pain
Neuropathic pain resulting from damage or dysfunction of the nervous system is a highly
debilitating chronic pain state and is often resistant to currently available treatments. It has …
debilitating chronic pain state and is often resistant to currently available treatments. It has …
Neuropathic pain
J Borzan, RA Meyer - Encyclopedia of Neuroscience, 2009 - pure.johnshopkins.edu
Certain diseases, chemotherapy, or nerve traumas can lead to pathology in the peripheral or
central nervous system that causes chronic neuropathic pain. Peripheral and central …
central nervous system that causes chronic neuropathic pain. Peripheral and central …
[HTML][HTML] Mediators of inflammation as targets for chronic pain treatment
M Lipnik-Stangelj - Mediators of inflammation, 2013 - ncbi.nlm.nih.gov
Treatment of chronic pain remains an unresolved problem in human medicine which greatly
impairs quality of life and prolongs treatment. Solving this problem is difficult due to a …
impairs quality of life and prolongs treatment. Solving this problem is difficult due to a …
[HTML][HTML] Novel therapies for the treatment of neuropathic pain: potential and pitfalls
Neuropathic pain affects more than one million people across the globe. The quality of life of
people suffering from neuropathic pain has been considerably declining due to the …
people suffering from neuropathic pain has been considerably declining due to the …
Pathophysiological mechanisms of neuropathic pain
A Truini, G Cruccu - Neurological Sciences, 2006 - Springer
It is largely acknowledged that multiple and complex pathophysiological mechanisms may
be at play in neuropathic pain. This short review summarises the current understanding of …
be at play in neuropathic pain. This short review summarises the current understanding of …
From the gender gap to neuroactive steroids: exploring multiple cases to further understand neuropathic pain
S Marinelli, R Coccurello - International Journal of Molecular Sciences, 2023 - mdpi.com
Neuropathic pain (NeuP) is still an intractable form of highly debilitating chronic pain,
resulting from a lesion or disease of the somatosensory nervous system [1]. It is well …
resulting from a lesion or disease of the somatosensory nervous system [1]. It is well …