[HTML][HTML] Data-independent acquisition mass spectrometry (DIA-MS) for proteomic applications in oncology

L Krasny, PH Huang - Molecular omics, 2021 - pubs.rsc.org
Data-independent acquisition mass spectrometry (DIA-MS) is a next generation proteomic
methodology that generates permanent digital proteome maps offering highly reproducible …

Clinical applications of mass spectrometry‐based proteomics in cancer: Where are we?

EL Boys, J Liu, PJ Robinson, RR Reddel - Proteomics, 2023 - Wiley Online Library
Tumor tissue processing methodologies in combination with data‐independent acquisition
mass spectrometry (DIA‐MS) have emerged that can comprehensively analyze the …

Advances in data‐independent acquisition mass spectrometry towards comprehensive digital proteome landscape

RB Kitata, JC Yang, YJ Chen - Mass spectrometry reviews, 2023 - Wiley Online Library
The data‐independent acquisition mass spectrometry (DIA‐MS) has rapidly evolved as a
powerful alternative for highly reproducible proteome profiling with a unique strength of …

DPHL: a DIA pan-human protein mass spectrometry library for robust biomarker discovery

T Zhu, Y Zhu, Y Xuan, H Gao, X Cai… - Genomics …, 2020 - academic.oup.com
To address the increasing need for detecting and validating protein biomarkers in clinical
specimens, mass spectrometry (MS)-based targeted proteomic techniques, including the …

Using data‐independent, high‐resolution mass spectrometry in protein biomarker research: perspectives and clinical applications

T Sajic, Y Liu, R Aebersold - PROTEOMICS–Clinical …, 2015 - Wiley Online Library
In medicine, there is an urgent need for protein biomarkers in a range of applications that
includes diagnostics, disease stratification, and therapeutic decisions. One of the main …

Mass spectrometry‐based targeted quantitative proteomics: achieving sensitive and reproducible detection of proteins

ES Boja, H Rodriguez - Proteomics, 2012 - Wiley Online Library
Traditional shotgun proteomics used to detect a mixture of hundreds to thousands of
proteins through mass spectrometric analysis, has been the standard approach in research …

Data‐independent acquisition mass spectrometry‐based proteomics and software tools: a glimpse in 2020

F Zhang, W Ge, G Ruan, X Cai, T Guo - Proteomics, 2020 - Wiley Online Library
This review provides a brief overview of the development of data‐independent acquisition
(DIA) mass spectrometry‐based proteomics and selected DIA data analysis tools. Various …

[HTML][HTML] Recent advances in mass spectrometry based clinical proteomics: applications to cancer research

A Macklin, S Khan, T Kislinger - Clinical proteomics, 2020 - Springer
Cancer biomarkers have transformed current practices in the oncology clinic. Continued
discovery and validation are crucial for improving early diagnosis, risk stratification, and …

Mass spectrometry technologies for proteomics

B Cañas, D López-Ferrer… - Briefings in …, 2006 - academic.oup.com
In the late 1980s, the advent of soft ionization techniques capable of generating stable gas
phase ions from thermally unstable biomolecules, namely matrix-assisted laser …

The evolving role of mass spectrometry in cancer biomarker discovery

P Wang, JR Whiteaker, AG Paulovich - Cancer biology & therapy, 2009 - Taylor & Francis
Although the field of mass spectrometry-based proteomics is still in its infancy, recent
developments in targeted proteomic techniques have left the field poised to impact the …