Melanoma is one of the most lethal and malignant cancers and its incidence is increasing
worldwide, and Japan is not an exception. Although there are numerous therapeutic options …

S-cysteinyldopa (5-S-CD) has been described as a tumour marker for the detection of
human metastatic melanoma. We investigated the clinical utility of a new and optimized …

5-S-Cysteinyldopa (5-SCD) in plasma and urine was determined by means of a newly
developed method. This method incorporates optimized conditions for blood collection and …

S-Cysteinyldopa (5-S-CD) has been used as a biochemical marker of melanoma
progression. In this study, we measured serum levels of 5-S-CD in 2648 samples taken from …

Early diagnosis of malignant melanoma is critical for effective treatment and reduced patient
mortality. However, current clinical and histological variables show limited accuracy in …

5-S-cysteinyldopa is a precursor of melanin. Its serum and urinary level can reflect
melanoma progression. In this study the concentration changes of 5-S-CD in melanomas of …

Background 5‐S‐cysteinyldopa (5‐S‐DC) is a precursor of melanin. Its serum and urinary
level can reflect melanoma progression. In this study we examined the concentration …

Tumor markers for metastatic melanoma have, so far, been infrequently used. Although
there is good evidence from several studies that protein S-100B serum measurement could …

In a series of 92 patients with malignant melanoma, clinical stage III or IV, both 5-S-
cysteinyldopa (5SCD) and 6-hydroxy-5-methoxyindole-2-carboxylic acid (6H5MI2C) were …

With the recent development of novel molecular targeted drugs for advanced stage
malignant melanoma (MM), including RAF and mitogen‐activated protein kinase kinase …