Remodeling of the arcuate nucleus energy-balance circuit is inhibited in obese mice
DEG McNay, N Briançon, MV Kokoeva… - The Journal of …, 2012 - Am Soc Clin Investig
In the CNS, the hypothalamic arcuate nucleus (ARN) energy-balance circuit plays a key role
in regulating body weight. Recent studies have shown that neurogenesis occurs in the adult …
in regulating body weight. Recent studies have shown that neurogenesis occurs in the adult …
Hypothalamic neural projections are permanently disrupted in diet-induced obese rats
The arcuate nucleus of the hypothalamus (ARH) is a key component of hypothalamic
pathways regulating energy balance, and leptin is required for normal development of ARH …
pathways regulating energy balance, and leptin is required for normal development of ARH …
Development of leptin‐sensitive circuits
SG Bouret, RB Simerly - Journal of neuroendocrinology, 2007 - Wiley Online Library
Energy homeostasis is achieved by the integration of peripheral metabolic signals by neural
circuits. The organisation and function of neural circuits regulating energy homeostasis has …
circuits. The organisation and function of neural circuits regulating energy homeostasis has …
Neonatal leptin exposure specifies innervation of presympathetic hypothalamic neurons and improves the metabolic status of leptin-deficient mice
K Bouyer, RB Simerly - Journal of Neuroscience, 2013 - Soc Neuroscience
The paraventricular nucleus of the hypothalamus (PVH) consists of distinct functional
compartments regulating neuroendocrine, behavioral, and autonomic activities that are …
compartments regulating neuroendocrine, behavioral, and autonomic activities that are …
Minireview: leptin and development of hypothalamic feeding circuits
SG Bouret, RB Simerly - Endocrinology, 2004 - academic.oup.com
The arcuate nucleus of the hypothalamus (ARH) is a critical component of the forebrain
pathways that regulate energy homeostasis, and it plays a particularly important role in …
pathways that regulate energy homeostasis, and it plays a particularly important role in …
[引用][C] Toward a new neurobiology of energy balance, appetite, and obesity: the anatomists weigh in
PE Sawchenko - Journal of Comparative Neurology, 1998 - Wiley Online Library
To paraphrase one who has worked long and well on the regulation of ingestive behavior, it
may be said that trying to study the neural control of eating is like trying to study vision …
may be said that trying to study the neural control of eating is like trying to study vision …
De novo neurogenesis in adult hypothalamus as a compensatory mechanism to regulate energy balance
AA Pierce, AW Xu - Journal of Neuroscience, 2010 - Soc Neuroscience
The ability to develop counter-regulatory mechanisms to maintain energy balance in
response to environmental and physiologic insults is essential for survival, but the …
response to environmental and physiologic insults is essential for survival, but the …
GABAergic RIP-Cre neurons in the arcuate nucleus selectively regulate energy expenditure
D Kong, Q Tong, C Ye, S Koda, PM Fuller, MJ Krashes… - Cell, 2012 - cell.com
Neural regulation of energy expenditure is incompletely understood. By genetically
disrupting GABAergic transmission in a cell-specific fashion, and by combining this with …
disrupting GABAergic transmission in a cell-specific fashion, and by combining this with …
How the brain regulates food intake and body weight: the role of leptin.
DG Baskin, JE Blevins, MW Schwartz - Journal of Pediatric …, 2001 - europepmc.org
The brain plays a key role in the regulation of energy homeostasis, balancing food intake
and energy expenditure to maintain adipose tissue mass. A widely accepted model …
and energy expenditure to maintain adipose tissue mass. A widely accepted model …
The geometry of leptin action in the brain: more complicated than a simple ARC
Leptin signals the repletion of fat stores, acting in the CNS to permit energy utilization by a
host of autonomic and neuroendocrine processes and to decrease feeding. While much …
host of autonomic and neuroendocrine processes and to decrease feeding. While much …