Myocardial fibrosis is characterized by excessive deposition of myocardial interstitial
collagen, abnormal distribution, and excessive proliferation of fibroblasts. According to the …

Myocardial fibrogenesis is initiated once the coordination between oxygen supply and
demand is disrupted in pressure overload-induced cardiac hypertrophy. Clinical …

Objective: The mechanism by which chronic myocardial edema causes cardiac dysfunction
is poorly understood. We hypothesized that myocardial edema triggers cardiac fibrosis …

Heart disease causing cardiac cell death due to ischemia–reperfusion injury is a major
cause of morbidity and mortality in the United States. Coronary heart disease and …

The pathomechanisms of myocardial fibrosis are incompletely understood. Coronary
microvessels (MV), interstitial reactions and focal myocardial lesions characterized by …

Colocalization of myocardial fibrosis and inflammatory cells in rats. - Abstract - Europe PMC
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Background Myocardial fibrosis plays an important role in the pathogenesis of hypertensive
cardiac dysfunction, and myocardial strain could detect early systolic abnormalities when left …

Changes in the composition of cardiac tissue develop in hypertensive patients with left
ventricular hypertrophy (ie, hypertensive heart disease) and lead to structural remodeling of …

Background Fibrosis is commonly found in association with cardiac hypertrophy and failure,
but the relation of the connective tissue response to the development of impaired cardiac …

Left ventricular pressure overload (LVPO) can develop from antecedent diseases such as
aortic valve stenosis and systemic hypertension and is characterized by accumulation of …