Sphingolipids are a family of lipid molecules produced through different pathways in
mammals. Sphingolipids are structural components of membranes, but in response to …

Metabolic disease, including obesity and type 2 diabetes, constitutes a major emerging
health crisis in Western nations. Although the symptoms and clinical pathology and …

Alterations in lipid metabolism may contribute to diabetic complications. Sphingolipids are
essential components of cell membranes and have essential roles in homeostasis and in the …

Sphingolipids play an important role in the development of diabetes, both type 1 and type 2
diabetes, as well as in the development of both micro-and macro-vascular complications …

Obesity is a growing worldwide problem, especially in developed countries. This disease
adversely affects the quality of life and notably contributes to the development of type 2 …

Sphingolipids are a specialized group of lipids essential to the composition of the plasma
membrane of many cell types; however, they are primarily localized within the nervous …

Many investigations suggest the pivotal role of sphingolipids in the pathogenesis of lifestyle
diseases such as myocardial infarction, hypertension, stroke, diabetes mellitus type 2 and …

One of the major global health and welfare issues is the treatment of obesity and associated
metabolic disorders, such as type 2 diabetes mellitus and nonalcoholic fatty liver disease …

Despite the advancements in modern medicine, there are still difficulties in diagnosing
common illnesses. The invasiveness and price of the tests used to follow up certain …

Sphingolipids, ubiquitously produced in all vertebrate cells, are biologically active lipids that
are the structural components of cell membranes. They also function as intracellular and …