In eukaryotes, the cellular functions are segregated to membrane-bound organelles. This
inherently requires sorting of metabolites to membrane-limited locations. Sorting the …

Rab proteins compose the largest family of small GTPases and control the different steps of
intracellular membrane traffic. More recently, they have been shown to also regulate cell …

One major challenge for contemporary biology is the elucidation of the molecular
mechanisms responsible for cellular organization. To generate and maintain its …

Rab GTPases are important regulators of intracellular membrane trafficking in eukaryotes.
Both activating and inactivating mutations in Rab genes have been identified and implicated …

Membrane trafficking between cell organelles by vesiculo-tubular carriers is crucial to the
existence of eukaryotic cells. Fundamental in ensuring that cargoes are delivered to their …

Membrane trafficking between organelles by vesiculotubular carriers is fundamental to the
existence of eukaryotic cells. Central in ensuring that cargoes are delivered to their correct …

Rab GTPases (Rabs) are small proteins that play crucial roles in vesicle transport and
membrane trafficking. Owing to their widespread functions in several steps of vesicle …

Rab proteins are important components of small GTPases and play crucial roles in
regulating intracellular transportation and cargo delivery. Maintaining the proper functions of …

The endoplasmic reticulum (ER) and Golgi membrane system have major roles in cell
signaling and regulation of the biosynthesis/transport of proteins and lipids in response to …

The RAB class of small GTPases includes the major regulators of intracellular
communication, which are involved in vesicle generation through fusion and fission, and …